A patient-specific model of virtual ablation for atrial fibrillation
The purpose of this study was to propose a patient-specific model of atrial fibrillation (AF) and apply it to virtual radiofrequency ablation (RFA). We obtained patient-specific geometries of the left atrium (LA) from CT data and constructed three-dimensional (3D) simulation models. A bidomain Court...
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| creator | Kwon, Soon-Sung Yun, Yong Hyun Hong, Seung-Bae Pak, Hui-Nam Shim, Eun Bo |
| description | The purpose of this study was to propose a patient-specific model of atrial fibrillation (AF) and apply it to virtual radiofrequency ablation (RFA). We obtained patient-specific geometries of the left atrium (LA) from CT data and constructed three-dimensional (3D) simulation models. A bidomain Courtemanche model was used to simulate the 3D electric waves on the LA surface, and an S1-S2 protocol was applied to induce AF in the model. To identify scar areas in the models, we converted clinically measured voltage data on the LA surface to the scar maps of the simulation model. Then, after initiation of AF, we applied the virtual ablation scheme to the model and investigated whether the AF was terminated by the scheme. The computed results of AF and ablation were similar to those of clinical observation, providing a clinically important simulation method for preclinical virtual trials of AF treatment. |
| doi_str_mv | 10.1109/EMBC.2013.6609802 |
| format | Conference Proceeding |
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We obtained patient-specific geometries of the left atrium (LA) from CT data and constructed three-dimensional (3D) simulation models. A bidomain Courtemanche model was used to simulate the 3D electric waves on the LA surface, and an S1-S2 protocol was applied to induce AF in the model. To identify scar areas in the models, we converted clinically measured voltage data on the LA surface to the scar maps of the simulation model. Then, after initiation of AF, we applied the virtual ablation scheme to the model and investigated whether the AF was terminated by the scheme. The computed results of AF and ablation were similar to those of clinical observation, providing a clinically important simulation method for preclinical virtual trials of AF treatment.</description><subject>Action Potentials</subject><subject>Atrial Fibrillation - physiopathology</subject><subject>Atrial Fibrillation - surgery</subject><subject>Biological system modeling</subject><subject>Catheter Ablation - methods</subject><subject>Computational modeling</subject><subject>Computer Simulation</subject><subject>Data models</subject><subject>Electric potential</subject><subject>Geometry</subject><subject>Heart Atria - pathology</subject><subject>Heart Atria - physiopathology</subject><subject>Humans</subject><subject>Mathematical model</subject><subject>Models, Cardiovascular</subject><subject>Solid modeling</subject><subject>User-Computer Interface</subject><issn>1094-687X</issn><issn>1557-170X</issn><issn>1558-4615</issn><isbn>1457702169</isbn><isbn>9781457702167</isbn><fulltext>true</fulltext><rsrctype>conference_proceeding</rsrctype><creationdate>2013</creationdate><recordtype>conference_proceeding</recordtype><sourceid>6IE</sourceid><sourceid>RIE</sourceid><sourceid>EIF</sourceid><recordid>eNo9kN1KAzEUhKMottY-gAiSF9iak_9c1lp_oOKNgnclyeZAZNtddreCb-_CVq_mMPNxYIaQa2ALAObu1q_3qwVnIBZaM2cZPyGXIJUxjIN2p2QKStlCalBnw82cLLQ1nxMy77ovxhgYrQUXF2TC5ZA666bkYUkb3-e074uuSTFjjnRXl6miNdLv3PYHX1EfqoGp9xTrlvq-zYOHObS5Gv0rco6-6tL8qDPy8bh-Xz0Xm7enl9VyU0QhXV-4iCVPMSJCDKULQRprUAlUIJOWzAUpbWASsQRlEnirnXDeIwdmnNBiRm7Hv80h7FK5bdq88-3P9q_OANyMQE4p_cfHscQviKZZBw</recordid><startdate>20130101</startdate><enddate>20130101</enddate><creator>Kwon, Soon-Sung</creator><creator>Yun, Yong Hyun</creator><creator>Hong, Seung-Bae</creator><creator>Pak, Hui-Nam</creator><creator>Shim, Eun Bo</creator><general>IEEE</general><scope>6IE</scope><scope>6IH</scope><scope>CBEJK</scope><scope>RIE</scope><scope>RIO</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope></search><sort><creationdate>20130101</creationdate><title>A patient-specific model of virtual ablation for atrial fibrillation</title><author>Kwon, Soon-Sung ; Yun, Yong Hyun ; Hong, Seung-Bae ; Pak, Hui-Nam ; Shim, Eun Bo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c349t-9cfd2eccff1cbd9bb4787f53f514e6409b448b04ffd157e1a86939aaf21079363</frbrgroupid><rsrctype>conference_proceedings</rsrctype><prefilter>conference_proceedings</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Action Potentials</topic><topic>Atrial Fibrillation - physiopathology</topic><topic>Atrial Fibrillation - surgery</topic><topic>Biological system modeling</topic><topic>Catheter Ablation - methods</topic><topic>Computational modeling</topic><topic>Computer Simulation</topic><topic>Data models</topic><topic>Electric potential</topic><topic>Geometry</topic><topic>Heart Atria - pathology</topic><topic>Heart Atria - physiopathology</topic><topic>Humans</topic><topic>Mathematical model</topic><topic>Models, Cardiovascular</topic><topic>Solid modeling</topic><topic>User-Computer Interface</topic><toplevel>online_resources</toplevel><creatorcontrib>Kwon, Soon-Sung</creatorcontrib><creatorcontrib>Yun, Yong Hyun</creatorcontrib><creatorcontrib>Hong, Seung-Bae</creatorcontrib><creatorcontrib>Pak, Hui-Nam</creatorcontrib><creatorcontrib>Shim, Eun Bo</creatorcontrib><collection>IEEE Electronic Library (IEL) Conference Proceedings</collection><collection>IEEE Proceedings Order Plan (POP) 1998-present by volume</collection><collection>IEEE Xplore All Conference Proceedings</collection><collection>IEEE Electronic Library (IEL)</collection><collection>IEEE Proceedings Order Plans (POP) 1998-present</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Kwon, Soon-Sung</au><au>Yun, Yong Hyun</au><au>Hong, Seung-Bae</au><au>Pak, Hui-Nam</au><au>Shim, Eun Bo</au><format>book</format><genre>proceeding</genre><ristype>CONF</ristype><atitle>A patient-specific model of virtual ablation for atrial fibrillation</atitle><btitle>2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)</btitle><stitle>EMBC</stitle><addtitle>Conf Proc IEEE Eng Med Biol Soc</addtitle><date>2013-01-01</date><risdate>2013</risdate><volume>2013</volume><spage>1522</spage><epage>1525</epage><pages>1522-1525</pages><issn>1094-687X</issn><issn>1557-170X</issn><eissn>1558-4615</eissn><eisbn>1457702169</eisbn><eisbn>9781457702167</eisbn><abstract>The purpose of this study was to propose a patient-specific model of atrial fibrillation (AF) and apply it to virtual radiofrequency ablation (RFA). We obtained patient-specific geometries of the left atrium (LA) from CT data and constructed three-dimensional (3D) simulation models. A bidomain Courtemanche model was used to simulate the 3D electric waves on the LA surface, and an S1-S2 protocol was applied to induce AF in the model. To identify scar areas in the models, we converted clinically measured voltage data on the LA surface to the scar maps of the simulation model. Then, after initiation of AF, we applied the virtual ablation scheme to the model and investigated whether the AF was terminated by the scheme. The computed results of AF and ablation were similar to those of clinical observation, providing a clinically important simulation method for preclinical virtual trials of AF treatment.</abstract><cop>United States</cop><pub>IEEE</pub><pmid>24109989</pmid><doi>10.1109/EMBC.2013.6609802</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | ISSN: 1094-687X |
| ispartof | 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2013, Vol.2013, p.1522-1525 |
| issn | 1094-687X 1557-170X 1558-4615 |
| language | eng |
| recordid | cdi_ieee_primary_6609802 |
| source | IEEE Electronic Library (IEL) Conference Proceedings |
| subjects | Action Potentials Atrial Fibrillation - physiopathology Atrial Fibrillation - surgery Biological system modeling Catheter Ablation - methods Computational modeling Computer Simulation Data models Electric potential Geometry Heart Atria - pathology Heart Atria - physiopathology Humans Mathematical model Models, Cardiovascular Solid modeling User-Computer Interface |
| title | A patient-specific model of virtual ablation for atrial fibrillation |
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