Numerical analysis of liquid-phase SH-SAW biosensor on quartz

This paper describes a numerical analysis for the shear horizontal surface acoustic wave (SH-SAW) immunoassay biosensor. A numerical calculation method which was proposed by Campbell and Jones has been generally used to calculate SAW propagation characteristics. In this paper, a numerical calculatio...

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Hauptverfasser:	Goto, Mikihiro, Yatsuda, Hiromi, Kondoh, Jun
Format:	Tagungsbericht
Sprache:	eng
Schlagworte:	biosensor Biosensors Gold Immune system immunoassay liquid-phase Liquids numerical analysis SH-SAW Surface acoustic waves viscosity sensitivity
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creator	Goto, Mikihiro Yatsuda, Hiromi Kondoh, Jun
description	This paper describes a numerical analysis for the shear horizontal surface acoustic wave (SH-SAW) immunoassay biosensor. A numerical calculation method which was proposed by Campbell and Jones has been generally used to calculate SAW propagation characteristics. In this paper, a numerical calculation method for SH-SA W propagation characteristics is proposed, which is an improved Campbell and Jones method involving an influence of liquid viscosity. In order to confirm the proposed numerical analysis, 250 MHz SH-SA W delay-lines on quartz substrates were tested using glycerol-water mixed liquids of different concentrations of 0, 10, 20 and 30 wt%. In the experiments, the velocity changes and attenuation changes of the SH-SA Ws were increased increment in glycerol concentrations as theoretically expected. Very good agreements between theoretical and experimental results were obtained.
doi_str_mv	10.1109/ULTSYM.2012.0527
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A numerical calculation method which was proposed by Campbell and Jones has been generally used to calculate SAW propagation characteristics. In this paper, a numerical calculation method for SH-SA W propagation characteristics is proposed, which is an improved Campbell and Jones method involving an influence of liquid viscosity. In order to confirm the proposed numerical analysis, 250 MHz SH-SA W delay-lines on quartz substrates were tested using glycerol-water mixed liquids of different concentrations of 0, 10, 20 and 30 wt%. In the experiments, the velocity changes and attenuation changes of the SH-SA Ws were increased increment in glycerol concentrations as theoretically expected. 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A numerical calculation method which was proposed by Campbell and Jones has been generally used to calculate SAW propagation characteristics. In this paper, a numerical calculation method for SH-SA W propagation characteristics is proposed, which is an improved Campbell and Jones method involving an influence of liquid viscosity. In order to confirm the proposed numerical analysis, 250 MHz SH-SA W delay-lines on quartz substrates were tested using glycerol-water mixed liquids of different concentrations of 0, 10, 20 and 30 wt%. In the experiments, the velocity changes and attenuation changes of the SH-SA Ws were increased increment in glycerol concentrations as theoretically expected. Very good agreements between theoretical and experimental results were obtained.</description><subject>biosensor</subject><subject>Biosensors</subject><subject>Gold</subject><subject>Immune system</subject><subject>immunoassay</subject><subject>liquid-phase</subject><subject>Liquids</subject><subject>numerical analysis</subject><subject>SH-SAW</subject><subject>Surface acoustic waves</subject><subject>viscosity sensitivity</subject><issn>1051-0117</issn><isbn>9781467345613</isbn><isbn>146734561X</isbn><isbn>9781467345606</isbn><isbn>9781467345620</isbn><isbn>1467345628</isbn><isbn>1467345601</isbn><fulltext>true</fulltext><rsrctype>conference_proceeding</rsrctype><creationdate>2012</creationdate><recordtype>conference_proceeding</recordtype><sourceid>6IE</sourceid><sourceid>RIE</sourceid><recordid>eNpVjD1PwzAUAI0AiapkR2LxH3B4z44_MjBUFbRIAYa0QkzVS-IKozRp42Yovx4kWJjubjnGbhBSRMjv1sWqfH9OJaBMQUt7xpLcOsyMVZk2YM7_NaoLNkHQKADRXrEkxk-AHwcL1kzY_cu480OoqeXUUXuKIfJ-y9twGEMj9h8UPS-Xopy98Sr00XexH3jf8cNIw_Hrml1uqY0--eOUrR8fVvOlKF4XT_NZIYLM8ChyhaqqdO7BW4_ONUjeOA1kMiupQVtXpEzlgNDm0mRAum50Q65xlBsHaspuf7_Be7_ZD2FHw2ljtJHSOPUNQkxLLw</recordid><startdate>201210</startdate><enddate>201210</enddate><creator>Goto, Mikihiro</creator><creator>Yatsuda, Hiromi</creator><creator>Kondoh, Jun</creator><general>IEEE</general><scope>6IE</scope><scope>6IH</scope><scope>CBEJK</scope><scope>RIE</scope><scope>RIO</scope></search><sort><creationdate>201210</creationdate><title>Numerical analysis of liquid-phase SH-SAW biosensor on quartz</title><author>Goto, Mikihiro ; Yatsuda, Hiromi ; Kondoh, Jun</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-i241t-9313bb59e0e7e188d1ae6850a6472ad17cba36b80a1792640a5cd5da8d8a96803</frbrgroupid><rsrctype>conference_proceedings</rsrctype><prefilter>conference_proceedings</prefilter><language>eng</language><creationdate>2012</creationdate><topic>biosensor</topic><topic>Biosensors</topic><topic>Gold</topic><topic>Immune system</topic><topic>immunoassay</topic><topic>liquid-phase</topic><topic>Liquids</topic><topic>numerical analysis</topic><topic>SH-SAW</topic><topic>Surface acoustic waves</topic><topic>viscosity sensitivity</topic><toplevel>online_resources</toplevel><creatorcontrib>Goto, Mikihiro</creatorcontrib><creatorcontrib>Yatsuda, Hiromi</creatorcontrib><creatorcontrib>Kondoh, Jun</creatorcontrib><collection>IEEE Electronic Library (IEL) Conference Proceedings</collection><collection>IEEE Proceedings Order Plan (POP) 1998-present by volume</collection><collection>IEEE Xplore All Conference Proceedings</collection><collection>IEEE Electronic Library (IEL)</collection><collection>IEEE Proceedings Order Plans (POP) 1998-present</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Goto, Mikihiro</au><au>Yatsuda, Hiromi</au><au>Kondoh, Jun</au><format>book</format><genre>proceeding</genre><ristype>CONF</ristype><atitle>Numerical analysis of liquid-phase SH-SAW biosensor on quartz</atitle><btitle>2012 IEEE International Ultrasonics Symposium</btitle><stitle>ULTSYM</stitle><date>2012-10</date><risdate>2012</risdate><spage>2110</spage><epage>2113</epage><pages>2110-2113</pages><issn>1051-0117</issn><isbn>9781467345613</isbn><isbn>146734561X</isbn><eisbn>9781467345606</eisbn><eisbn>9781467345620</eisbn><eisbn>1467345628</eisbn><eisbn>1467345601</eisbn><abstract>This paper describes a numerical analysis for the shear horizontal surface acoustic wave (SH-SAW) immunoassay biosensor. A numerical calculation method which was proposed by Campbell and Jones has been generally used to calculate SAW propagation characteristics. In this paper, a numerical calculation method for SH-SA W propagation characteristics is proposed, which is an improved Campbell and Jones method involving an influence of liquid viscosity. In order to confirm the proposed numerical analysis, 250 MHz SH-SA W delay-lines on quartz substrates were tested using glycerol-water mixed liquids of different concentrations of 0, 10, 20 and 30 wt%. In the experiments, the velocity changes and attenuation changes of the SH-SA Ws were increased increment in glycerol concentrations as theoretically expected. Very good agreements between theoretical and experimental results were obtained.</abstract><pub>IEEE</pub><doi>10.1109/ULTSYM.2012.0527</doi><tpages>4</tpages></addata></record>
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subjects	biosensor Biosensors Gold Immune system immunoassay liquid-phase Liquids numerical analysis SH-SAW Surface acoustic waves viscosity sensitivity
title	Numerical analysis of liquid-phase SH-SAW biosensor on quartz
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