Indication of abnormal peripheral sensory processing of rotational stimulation in ADHD
Attention Deficit Hyperactivity Disorder (ADHD) has been associated with motor abnormalities. Given the importance of the vestibular system in motor control, the investigation of the peripheral vestibular response is a promising area of ADHD research, which could lead to an improved understanding an...
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| container_title | 2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society |
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| creator | Grossman, I. Lithgow, B. |
| description | Attention Deficit Hyperactivity Disorder (ADHD) has been associated with motor abnormalities. Given the importance of the vestibular system in motor control, the investigation of the peripheral vestibular response is a promising area of ADHD research, which could lead to an improved understanding and management of the disorder. This study aimed to investigate the evoked peripheral vestibular response to rotational stimuli in ADHD affected adults, using Electrovestibulography (EVestG). Data was collected from 6 ADHD affected adults (2 males, 4 females) and contrasted with that of a Control group comprised of 30 individuals (10 males, 20 females). Raw data was 120 Hz high pass filtered and analyzed using the Neural Event Extraction Routine to identify local field potentials, which represent the summed activity of the components of the inner ear. The inter field potential intervals (IFPI) were calculated as the time intervals between field potentials. Analysis of the IFPI indicated that the ADHD group exhibited significantly shorter periods between field potentials generated in the right ear during left rotational acceleration than Controls (unpaired, two-tailed Student's t-test assuming unequal variance, p |
| doi_str_mv | 10.1109/EMBC.2012.6347008 |
| format | Article |
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Given the importance of the vestibular system in motor control, the investigation of the peripheral vestibular response is a promising area of ADHD research, which could lead to an improved understanding and management of the disorder. This study aimed to investigate the evoked peripheral vestibular response to rotational stimuli in ADHD affected adults, using Electrovestibulography (EVestG). Data was collected from 6 ADHD affected adults (2 males, 4 females) and contrasted with that of a Control group comprised of 30 individuals (10 males, 20 females). Raw data was 120 Hz high pass filtered and analyzed using the Neural Event Extraction Routine to identify local field potentials, which represent the summed activity of the components of the inner ear. The inter field potential intervals (IFPI) were calculated as the time intervals between field potentials. Analysis of the IFPI indicated that the ADHD group exhibited significantly shorter periods between field potentials generated in the right ear during left rotational acceleration than Controls (unpaired, two-tailed Student's t-test assuming unequal variance, p<;0.05). However there was no significant difference between groups for left ear signal during right rotational acceleration. This preliminary study provides an indication as to the possibility of lateralized, abnormal inner ear responses to kinematic stimuli in the ADHD affected population. However, further studies are required to validate and elucidate this data.</description><identifier>ISSN: 1094-687X</identifier><identifier>ISSN: 1557-170X</identifier><identifier>ISBN: 1424441196</identifier><identifier>ISBN: 9781424441198</identifier><identifier>EISSN: 1558-4615</identifier><identifier>EISBN: 9781457717871</identifier><identifier>EISBN: 1457717875</identifier><identifier>DOI: 10.1109/EMBC.2012.6347008</identifier><identifier>PMID: 23366969</identifier><language>eng</language><publisher>United States: IEEE</publisher><subject>Acceleration ; Adult ; Aged ; Attention Deficit Disorder with Hyperactivity - complications ; Attention Deficit Disorder with Hyperactivity - physiopathology ; Ear ; Female ; Humans ; Irrigation ; Kinematics ; Male ; Medical diagnostic imaging ; Middle Aged ; Motion Perception ; Neurons ; Physical Stimulation - methods ; Psychiatry ; Rotation ; Vestibular Diseases - etiology ; Vestibular Diseases - physiopathology ; Vestibule, Labyrinth - physiopathology</subject><ispartof>2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2012-01, Vol.2012, p.4668-4671</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://ieeexplore.ieee.org/document/6347008$$EHTML$$P50$$Gieee$$H</linktohtml><link.rule.ids>310,311,781,785,790,791,2059,27930,54925</link.rule.ids><linktorsrc>$$Uhttps://ieeexplore.ieee.org/document/6347008$$EView_record_in_IEEE$$FView_record_in_$$GIEEE</linktorsrc><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23366969$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Grossman, I.</creatorcontrib><creatorcontrib>Lithgow, B.</creatorcontrib><title>Indication of abnormal peripheral sensory processing of rotational stimulation in ADHD</title><title>2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society</title><addtitle>EMBC</addtitle><addtitle>Conf Proc IEEE Eng Med Biol Soc</addtitle><description>Attention Deficit Hyperactivity Disorder (ADHD) has been associated with motor abnormalities. Given the importance of the vestibular system in motor control, the investigation of the peripheral vestibular response is a promising area of ADHD research, which could lead to an improved understanding and management of the disorder. This study aimed to investigate the evoked peripheral vestibular response to rotational stimuli in ADHD affected adults, using Electrovestibulography (EVestG). Data was collected from 6 ADHD affected adults (2 males, 4 females) and contrasted with that of a Control group comprised of 30 individuals (10 males, 20 females). Raw data was 120 Hz high pass filtered and analyzed using the Neural Event Extraction Routine to identify local field potentials, which represent the summed activity of the components of the inner ear. The inter field potential intervals (IFPI) were calculated as the time intervals between field potentials. Analysis of the IFPI indicated that the ADHD group exhibited significantly shorter periods between field potentials generated in the right ear during left rotational acceleration than Controls (unpaired, two-tailed Student's t-test assuming unequal variance, p<;0.05). However there was no significant difference between groups for left ear signal during right rotational acceleration. This preliminary study provides an indication as to the possibility of lateralized, abnormal inner ear responses to kinematic stimuli in the ADHD affected population. However, further studies are required to validate and elucidate this data.</description><subject>Acceleration</subject><subject>Adult</subject><subject>Aged</subject><subject>Attention Deficit Disorder with Hyperactivity - complications</subject><subject>Attention Deficit Disorder with Hyperactivity - physiopathology</subject><subject>Ear</subject><subject>Female</subject><subject>Humans</subject><subject>Irrigation</subject><subject>Kinematics</subject><subject>Male</subject><subject>Medical diagnostic imaging</subject><subject>Middle Aged</subject><subject>Motion Perception</subject><subject>Neurons</subject><subject>Physical Stimulation - methods</subject><subject>Psychiatry</subject><subject>Rotation</subject><subject>Vestibular Diseases - etiology</subject><subject>Vestibular Diseases - physiopathology</subject><subject>Vestibule, Labyrinth - physiopathology</subject><issn>1094-687X</issn><issn>1557-170X</issn><issn>1558-4615</issn><isbn>1424441196</isbn><isbn>9781424441198</isbn><isbn>9781457717871</isbn><isbn>1457717875</isbn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>6IE</sourceid><sourceid>RIE</sourceid><sourceid>EIF</sourceid><recordid>eNo9kMtOAkEQRdtXBJEPMCZmfmCwavq9REAhwbhR4470DN3ahnmke1jw9w6C1qYquaduci8hNwgjRND3s-eHySgDzEaCMgmgTshQS4WMS4lSSTwlfeRcpUwgPyNXyDLGGKIW550AmqVCyY8eGcb4Dd0oVBTYJelllAqhhe6T90W19oVpfV0ltUtMXtWhNJukscE3XzZ0Z7RVrMMuaUJd2Bh99bknQ93-fu2B1pfbzcHDV8l4Op9ekwtnNtEOj3tA3h5nr5N5unx5WkzGy9RTytrUSSYNUGpRS6uccMh1bkDmIKnVvDDSGirQMXAZuC624EZxzjDnhVyDoANyd_Bttnlp16sm-NKE3eovYAfcHgBvrf2Xj3XSH9yeYcc</recordid><startdate>20120101</startdate><enddate>20120101</enddate><creator>Grossman, I.</creator><creator>Lithgow, B.</creator><general>IEEE</general><scope>6IE</scope><scope>6IH</scope><scope>CBEJK</scope><scope>RIE</scope><scope>RIO</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope></search><sort><creationdate>20120101</creationdate><title>Indication of abnormal peripheral sensory processing of rotational stimulation in ADHD</title><author>Grossman, I. ; Lithgow, B.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-i334t-f747a033e197e8f6f159ba07b073e95ca7ea361f40f20f45765a85541b5c7d063</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Acceleration</topic><topic>Adult</topic><topic>Aged</topic><topic>Attention Deficit Disorder with Hyperactivity - complications</topic><topic>Attention Deficit Disorder with Hyperactivity - physiopathology</topic><topic>Ear</topic><topic>Female</topic><topic>Humans</topic><topic>Irrigation</topic><topic>Kinematics</topic><topic>Male</topic><topic>Medical diagnostic imaging</topic><topic>Middle Aged</topic><topic>Motion Perception</topic><topic>Neurons</topic><topic>Physical Stimulation - methods</topic><topic>Psychiatry</topic><topic>Rotation</topic><topic>Vestibular Diseases - etiology</topic><topic>Vestibular Diseases - physiopathology</topic><topic>Vestibule, Labyrinth - physiopathology</topic><toplevel>online_resources</toplevel><creatorcontrib>Grossman, I.</creatorcontrib><creatorcontrib>Lithgow, B.</creatorcontrib><collection>IEEE Electronic Library (IEL) Conference Proceedings</collection><collection>IEEE Proceedings Order Plan (POP) 1998-present by volume</collection><collection>IEEE Xplore All Conference Proceedings</collection><collection>IEEE Electronic Library (IEL)</collection><collection>IEEE Proceedings Order Plans (POP) 1998-present</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><jtitle>2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Grossman, I.</au><au>Lithgow, B.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Indication of abnormal peripheral sensory processing of rotational stimulation in ADHD</atitle><jtitle>2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society</jtitle><stitle>EMBC</stitle><addtitle>Conf Proc IEEE Eng Med Biol Soc</addtitle><date>2012-01-01</date><risdate>2012</risdate><volume>2012</volume><spage>4668</spage><epage>4671</epage><pages>4668-4671</pages><issn>1094-687X</issn><issn>1557-170X</issn><eissn>1558-4615</eissn><isbn>1424441196</isbn><isbn>9781424441198</isbn><eisbn>9781457717871</eisbn><eisbn>1457717875</eisbn><abstract>Attention Deficit Hyperactivity Disorder (ADHD) has been associated with motor abnormalities. Given the importance of the vestibular system in motor control, the investigation of the peripheral vestibular response is a promising area of ADHD research, which could lead to an improved understanding and management of the disorder. This study aimed to investigate the evoked peripheral vestibular response to rotational stimuli in ADHD affected adults, using Electrovestibulography (EVestG). Data was collected from 6 ADHD affected adults (2 males, 4 females) and contrasted with that of a Control group comprised of 30 individuals (10 males, 20 females). Raw data was 120 Hz high pass filtered and analyzed using the Neural Event Extraction Routine to identify local field potentials, which represent the summed activity of the components of the inner ear. The inter field potential intervals (IFPI) were calculated as the time intervals between field potentials. Analysis of the IFPI indicated that the ADHD group exhibited significantly shorter periods between field potentials generated in the right ear during left rotational acceleration than Controls (unpaired, two-tailed Student's t-test assuming unequal variance, p<;0.05). However there was no significant difference between groups for left ear signal during right rotational acceleration. This preliminary study provides an indication as to the possibility of lateralized, abnormal inner ear responses to kinematic stimuli in the ADHD affected population. However, further studies are required to validate and elucidate this data.</abstract><cop>United States</cop><pub>IEEE</pub><pmid>23366969</pmid><doi>10.1109/EMBC.2012.6347008</doi><tpages>4</tpages></addata></record> |
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| ispartof | 2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2012-01, Vol.2012, p.4668-4671 |
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| language | eng |
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| source | IEEE Electronic Library (IEL) Conference Proceedings |
| subjects | Acceleration Adult Aged Attention Deficit Disorder with Hyperactivity - complications Attention Deficit Disorder with Hyperactivity - physiopathology Ear Female Humans Irrigation Kinematics Male Medical diagnostic imaging Middle Aged Motion Perception Neurons Physical Stimulation - methods Psychiatry Rotation Vestibular Diseases - etiology Vestibular Diseases - physiopathology Vestibule, Labyrinth - physiopathology |
| title | Indication of abnormal peripheral sensory processing of rotational stimulation in ADHD |
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