Low voltage digitally programmable gain and bandwidth fully differential CMOS neural amplifier

In this paper, a low voltage fully differential digitally programmable gain and bandwidth CMOS neural amplifier has been presented. The design is suitable for LFP and spikes signals. The neural amplifier has been simulated using LTspice with a CMOS technology of 90nm provided from MOSIS and power supply of 1.2V. The amplifier gain could be programmed from 30 dB to 70 dB, with a total power consumption of 12.48 μW, and an input referred noise of 6μV/Hz 1/2 over LFP signal range and 154 nV/Hz 1/2 for spikes signals. Moreover, the lower cutoff frequency of the amplifier can be digitally programmed using a new pseudo-resistor structure.