Unsupervised wrinkle detection in reflectance confocal microscopy images of the human skin

Reflectance confocal microscopy (RCM) is a non-invasive and in-vivo imaging modality, which can take images from different depths of the human skin. A challenging problem is to detect a clinically important subsurface section of the skin, the Dermis/Epidermis junction, in RCM images. This is a tough...

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Hauptverfasser: Sourati, J., Brooks, D. H., Dy, J. G., Ataer-Cansizoglu, E., Erdogmus, D., Rajadhyaksha, M.
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Brooks, D. H.
Dy, J. G.
Ataer-Cansizoglu, E.
Erdogmus, D.
Rajadhyaksha, M.
description Reflectance confocal microscopy (RCM) is a non-invasive and in-vivo imaging modality, which can take images from different depths of the human skin. A challenging problem is to detect a clinically important subsurface section of the skin, the Dermis/Epidermis junction, in RCM images. This is a tough problem because of the huge variation of texture and intensity features across both intersubject and intrasubject tissues. On the other hand, there's almost no wrinkle-free part of the skin. This well-known phenomenon can be used as a histological clue for guessing the probability of being Dermis or Epidermis in the neighboring regions. In this paper, we develop a two-step wrinkle detector for RCM images. By analyzing the results on different RCM images, we conclude it has high sensitivity and specificity, but a relatively lower Jaccard index.
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source IEEE Electronic Library (IEL) Conference Proceedings
subjects Dermis-Epidermis junction
Epidermis
Humans
Indexes
Junctions
Microscopy
Reflectance confocal microscopy
Reflectivity
wrinkle detection
title Unsupervised wrinkle detection in reflectance confocal microscopy images of the human skin
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