Design of a microfeature scaffold for tissue engineering
This paper describes a microfeature scaffold that is being developed for tissue engineering. Typically, cells are grown on scaffolds that are designed to influence and direct their phenotype. By changing one or more properties of the scaffold, such as topography, it is possible to affect cellular ph...
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creator | Senderling, B M Mortell, H M Cezeaux, J L Gettens, R T Rust, M J |
description | This paper describes a microfeature scaffold that is being developed for tissue engineering. Typically, cells are grown on scaffolds that are designed to influence and direct their phenotype. By changing one or more properties of the scaffold, such as topography, it is possible to affect cellular phenotypes, including adhesion, orientation and function. In this work, the width of microscale patterns on a polydimethylsiloxane scaffold will be varied to determine its effect on the orientation of cells in culture. If successful, this work may be applied toward research for the development of engineered tissues. |
doi_str_mv | 10.1109/NEBC.2011.5778536 |
format | Conference Proceeding |
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ispartof | 2011 IEEE 37th Annual Northeast Bioengineering Conference (NEBEC), 2011, p.1-2 |
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source | IEEE Electronic Library (IEL) Conference Proceedings |
subjects | Cells (biology) Fabrication Microscopy Software Surface topography Tissue engineering |
title | Design of a microfeature scaffold for tissue engineering |
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