Under rolling loads preliminary research on solute transport in articular cartilage
The solute transport in vivo is an important biological behavior within the avascular extracellular matrix of articular cartilage. Mechanical condition drives the cartilage to obtain nutrition and exclude waste during daily activities. The investigation of the transport behavior within the tissue is...
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creator | Dan Zhao Chunqiu Zhang Zhenmin Fan Junxia Gao Liping Jin Kexue Jiang |
description | The solute transport in vivo is an important biological behavior within the avascular extracellular matrix of articular cartilage. Mechanical condition drives the cartilage to obtain nutrition and exclude waste during daily activities. The investigation of the transport behavior within the tissue is important to the understanding of the mechanisms of nutritional transport and mechanosignal transduction in cartilage. Under rolling loads, the solute transport within articular cartilage was preliminarily researched using the fluorescence detector to observe solute transport. In experiments, the compression rate of rolling loading is about 20%, rolling speed is 10cm / s, with experimental time respectively are 50s, 100s, and 5 min. Compared with the control group, the results show that the rolling load promoted the solute transport within articular cartilage. Although the exact promotion mechanism is unclear, the rolling loading may provide a potential load to enhance the solute transport, and may be applied to cartilage tissue engineering. |
doi_str_mv | 10.1109/BMEI.2010.5639584 |
format | Conference Proceeding |
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Mechanical condition drives the cartilage to obtain nutrition and exclude waste during daily activities. The investigation of the transport behavior within the tissue is important to the understanding of the mechanisms of nutritional transport and mechanosignal transduction in cartilage. Under rolling loads, the solute transport within articular cartilage was preliminarily researched using the fluorescence detector to observe solute transport. In experiments, the compression rate of rolling loading is about 20%, rolling speed is 10cm / s, with experimental time respectively are 50s, 100s, and 5 min. Compared with the control group, the results show that the rolling load promoted the solute transport within articular cartilage. Although the exact promotion mechanism is unclear, the rolling loading may provide a potential load to enhance the solute transport, and may be applied to cartilage tissue engineering.</description><identifier>ISSN: 1948-2914</identifier><identifier>ISBN: 1424464951</identifier><identifier>ISBN: 9781424464951</identifier><identifier>EISSN: 1948-2922</identifier><identifier>EISBN: 9781424464975</identifier><identifier>EISBN: 1424464986</identifier><identifier>EISBN: 1424464978</identifier><identifier>EISBN: 9781424464982</identifier><identifier>DOI: 10.1109/BMEI.2010.5639584</identifier><language>eng</language><publisher>IEEE</publisher><subject>articular cartilage ; device ; Fluorescence ; Knee ; Loading ; Microscopy ; rolling loading ; solute transport ; Surface treatment ; Training</subject><ispartof>2010 3rd International Conference on Biomedical Engineering and Informatics, 2010, Vol.4, p.1624-1626</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://ieeexplore.ieee.org/document/5639584$$EHTML$$P50$$Gieee$$H</linktohtml><link.rule.ids>309,310,780,784,789,790,2056,27924,54919</link.rule.ids><linktorsrc>$$Uhttps://ieeexplore.ieee.org/document/5639584$$EView_record_in_IEEE$$FView_record_in_$$GIEEE</linktorsrc></links><search><creatorcontrib>Dan Zhao</creatorcontrib><creatorcontrib>Chunqiu Zhang</creatorcontrib><creatorcontrib>Zhenmin Fan</creatorcontrib><creatorcontrib>Junxia Gao</creatorcontrib><creatorcontrib>Liping Jin</creatorcontrib><creatorcontrib>Kexue Jiang</creatorcontrib><title>Under rolling loads preliminary research on solute transport in articular cartilage</title><title>2010 3rd International Conference on Biomedical Engineering and Informatics</title><addtitle>BMEI</addtitle><description>The solute transport in vivo is an important biological behavior within the avascular extracellular matrix of articular cartilage. 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Although the exact promotion mechanism is unclear, the rolling loading may provide a potential load to enhance the solute transport, and may be applied to cartilage tissue engineering.</description><subject>articular cartilage</subject><subject>device</subject><subject>Fluorescence</subject><subject>Knee</subject><subject>Loading</subject><subject>Microscopy</subject><subject>rolling loading</subject><subject>solute transport</subject><subject>Surface treatment</subject><subject>Training</subject><issn>1948-2914</issn><issn>1948-2922</issn><isbn>1424464951</isbn><isbn>9781424464951</isbn><isbn>9781424464975</isbn><isbn>1424464986</isbn><isbn>1424464978</isbn><isbn>9781424464982</isbn><fulltext>true</fulltext><rsrctype>conference_proceeding</rsrctype><creationdate>2010</creationdate><recordtype>conference_proceeding</recordtype><sourceid>6IE</sourceid><sourceid>RIE</sourceid><recordid>eNo9kMtOwzAQRc1LopR-AGLjH0jxM46XUBWoVMQCuq4mzqQYuU5kpwv-niAKs7lzdaTR0RByw9mcc2bvHl6Wq7lgY9WltLpSJ2RmTcWVUKpU1uhTMuFWVYWwQpyRqz-g-fk_4OqSzHL-ZOMoLbQxE_K2iQ0mmroQfNzR0EGTaZ8w-L2PkL5owoyQ3AftIs1dOAxIhwQx910aqI8U0uDdIUCi7mcNsMNrctFCyDg75pRsHpfvi-di_fq0WtyvC8-NHgp0DkdbbFFXxoqSO92CFDVq7bStBWtQyZLVtqqdYqZ1QqAEcLUcMVgjp-T2965HxG2f_H4U3h7_I78B6nJW2A</recordid><startdate>201010</startdate><enddate>201010</enddate><creator>Dan Zhao</creator><creator>Chunqiu Zhang</creator><creator>Zhenmin Fan</creator><creator>Junxia Gao</creator><creator>Liping Jin</creator><creator>Kexue Jiang</creator><general>IEEE</general><scope>6IE</scope><scope>6IL</scope><scope>CBEJK</scope><scope>RIE</scope><scope>RIL</scope></search><sort><creationdate>201010</creationdate><title>Under rolling loads preliminary research on solute transport in articular cartilage</title><author>Dan Zhao ; Chunqiu Zhang ; Zhenmin Fan ; Junxia Gao ; Liping Jin ; Kexue Jiang</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-i175t-ecce292efe5879261c5fa32be55c59b20de4360b98bc407fc22e3aacb3c59a973</frbrgroupid><rsrctype>conference_proceedings</rsrctype><prefilter>conference_proceedings</prefilter><language>eng</language><creationdate>2010</creationdate><topic>articular cartilage</topic><topic>device</topic><topic>Fluorescence</topic><topic>Knee</topic><topic>Loading</topic><topic>Microscopy</topic><topic>rolling loading</topic><topic>solute transport</topic><topic>Surface treatment</topic><topic>Training</topic><toplevel>online_resources</toplevel><creatorcontrib>Dan Zhao</creatorcontrib><creatorcontrib>Chunqiu Zhang</creatorcontrib><creatorcontrib>Zhenmin Fan</creatorcontrib><creatorcontrib>Junxia Gao</creatorcontrib><creatorcontrib>Liping Jin</creatorcontrib><creatorcontrib>Kexue Jiang</creatorcontrib><collection>IEEE Electronic Library (IEL) Conference Proceedings</collection><collection>IEEE Proceedings Order Plan All Online (POP All Online) 1998-present by volume</collection><collection>IEEE Xplore All Conference Proceedings</collection><collection>IEEE Electronic Library (IEL)</collection><collection>IEEE Proceedings Order Plans (POP All) 1998-Present</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Dan Zhao</au><au>Chunqiu Zhang</au><au>Zhenmin Fan</au><au>Junxia Gao</au><au>Liping Jin</au><au>Kexue Jiang</au><format>book</format><genre>proceeding</genre><ristype>CONF</ristype><atitle>Under rolling loads preliminary research on solute transport in articular cartilage</atitle><btitle>2010 3rd International Conference on Biomedical Engineering and Informatics</btitle><stitle>BMEI</stitle><date>2010-10</date><risdate>2010</risdate><volume>4</volume><spage>1624</spage><epage>1626</epage><pages>1624-1626</pages><issn>1948-2914</issn><eissn>1948-2922</eissn><isbn>1424464951</isbn><isbn>9781424464951</isbn><eisbn>9781424464975</eisbn><eisbn>1424464986</eisbn><eisbn>1424464978</eisbn><eisbn>9781424464982</eisbn><abstract>The solute transport in vivo is an important biological behavior within the avascular extracellular matrix of articular cartilage. Mechanical condition drives the cartilage to obtain nutrition and exclude waste during daily activities. The investigation of the transport behavior within the tissue is important to the understanding of the mechanisms of nutritional transport and mechanosignal transduction in cartilage. Under rolling loads, the solute transport within articular cartilage was preliminarily researched using the fluorescence detector to observe solute transport. In experiments, the compression rate of rolling loading is about 20%, rolling speed is 10cm / s, with experimental time respectively are 50s, 100s, and 5 min. Compared with the control group, the results show that the rolling load promoted the solute transport within articular cartilage. Although the exact promotion mechanism is unclear, the rolling loading may provide a potential load to enhance the solute transport, and may be applied to cartilage tissue engineering.</abstract><pub>IEEE</pub><doi>10.1109/BMEI.2010.5639584</doi><tpages>3</tpages></addata></record> |
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identifier | ISSN: 1948-2914 |
ispartof | 2010 3rd International Conference on Biomedical Engineering and Informatics, 2010, Vol.4, p.1624-1626 |
issn | 1948-2914 1948-2922 |
language | eng |
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source | IEEE Electronic Library (IEL) Conference Proceedings |
subjects | articular cartilage device Fluorescence Knee Loading Microscopy rolling loading solute transport Surface treatment Training |
title | Under rolling loads preliminary research on solute transport in articular cartilage |
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