Lab-on-a-chip for the isolation and characterization of circulating tumor cells
A smart miniaturized system is being proposed for the isolation and characterization of circulating tumor cells (CTCs) directly from blood. Different microfluidic modules have been designed for cell enrichment and -counting, multiplex mRNA amplification as well as DNA detection. With the different m...
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| Veröffentlicht in: | 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology 2010-01, Vol.2010, p.292-294 |
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| container_title | 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology |
| container_volume | 2010 |
| creator | Stakenborg, Tim Chengxu Liu Henry, Olivier O'Sullivan, Ciara K Fermer, Christian Roeser, Tina Ritzi-Lehnert, Marion Hauch, Sigfried Borgen, Elin Laddach, Nadja Lagae, Liesbet |
| description | A smart miniaturized system is being proposed for the isolation and characterization of circulating tumor cells (CTCs) directly from blood. Different microfluidic modules have been designed for cell enrichment and -counting, multiplex mRNA amplification as well as DNA detection. With the different modules at hand, future effort will focus on the integration of the modules in a fully automated, single platform. |
| doi_str_mv | 10.1109/IEMBS.2010.5627655 |
| format | Article |
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| identifier | ISSN: 1094-687X |
| ispartof | 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology, 2010-01, Vol.2010, p.292-294 |
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| source | IEEE Electronic Library (IEL) Conference Proceedings |
| subjects | Cell Separation - instrumentation Cell Separation - methods Cytophotometry - instrumentation Cytophotometry - methods DNA DNA, Neoplasm - isolation & purification Humans Lab-On-A-Chip Devices Magnetic particles Magnetic sensors Magnetic separation Microfluidics Neoplasms - blood Neoplasms - genetics Neoplasms - pathology Neoplastic Cells, Circulating Polymerase Chain Reaction - instrumentation Polymerase Chain Reaction - methods Tumors |
| title | Lab-on-a-chip for the isolation and characterization of circulating tumor cells |
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