Implantable Flexible-Coiled Wireless Intraocular Pressure Sensor
This work presents an implantable wireless passive pressure sensor for long-range continuous intraocular pressure (IOP) monitoring of glaucoma patients. The sensor is microfabricated with use of parylene C (poly-chloro-p-xylylene) to create a flexible coil substrate that can be folded during implant...
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creator | Po-Jui Chen Saati, S. Varma, R. Humayun, M.S. Yu-Chong Tai |
description | This work presents an implantable wireless passive pressure sensor for long-range continuous intraocular pressure (IOP) monitoring of glaucoma patients. The sensor is microfabricated with use of parylene C (poly-chloro-p-xylylene) to create a flexible coil substrate that can be folded during implantation for suture-less minimally invasive surgery, while stretched back without damage for enhanced inductive sensor-reader coil coupling and the corresponding sensing signal. Extensive device characterizations including on-bench testing and in vivo and ex vivo animal studies verify the device feasibility in both engineering (1 mmHg pressure sensing accuracy and 2 cm sensing distance) and surgical (robust fixation to the iris and long-term biocompatibility in the intraocular environment) aspects, all meeting specifications for future practical implementation of such IOP sensing technology. |
doi_str_mv | 10.1109/MEMSYS.2009.4805364 |
format | Conference Proceeding |
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The sensor is microfabricated with use of parylene C (poly-chloro-p-xylylene) to create a flexible coil substrate that can be folded during implantation for suture-less minimally invasive surgery, while stretched back without damage for enhanced inductive sensor-reader coil coupling and the corresponding sensing signal. Extensive device characterizations including on-bench testing and in vivo and ex vivo animal studies verify the device feasibility in both engineering (1 mmHg pressure sensing accuracy and 2 cm sensing distance) and surgical (robust fixation to the iris and long-term biocompatibility in the intraocular environment) aspects, all meeting specifications for future practical implementation of such IOP sensing technology.</description><identifier>ISSN: 1084-6999</identifier><identifier>ISBN: 1424429773</identifier><identifier>ISBN: 9781424429776</identifier><identifier>EISBN: 1424429781</identifier><identifier>EISBN: 9781424429783</identifier><identifier>DOI: 10.1109/MEMSYS.2009.4805364</identifier><language>eng</language><publisher>IEEE</publisher><subject>Animals ; Coils ; In vivo ; Iris ; Minimally invasive surgery ; Patient monitoring ; Robustness ; Sensor phenomena and characterization ; Testing ; Wireless sensor networks</subject><ispartof>2009 IEEE 22nd International Conference on Micro Electro Mechanical Systems, 2009, p.244-247</ispartof><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://ieeexplore.ieee.org/document/4805364$$EHTML$$P50$$Gieee$$H</linktohtml><link.rule.ids>309,310,776,780,785,786,2052,27902,54895</link.rule.ids><linktorsrc>$$Uhttps://ieeexplore.ieee.org/document/4805364$$EView_record_in_IEEE$$FView_record_in_$$GIEEE</linktorsrc></links><search><creatorcontrib>Po-Jui Chen</creatorcontrib><creatorcontrib>Saati, S.</creatorcontrib><creatorcontrib>Varma, R.</creatorcontrib><creatorcontrib>Humayun, M.S.</creatorcontrib><creatorcontrib>Yu-Chong Tai</creatorcontrib><title>Implantable Flexible-Coiled Wireless Intraocular Pressure Sensor</title><title>2009 IEEE 22nd International Conference on Micro Electro Mechanical Systems</title><addtitle>MEMSYS</addtitle><description>This work presents an implantable wireless passive pressure sensor for long-range continuous intraocular pressure (IOP) monitoring of glaucoma patients. 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Extensive device characterizations including on-bench testing and in vivo and ex vivo animal studies verify the device feasibility in both engineering (1 mmHg pressure sensing accuracy and 2 cm sensing distance) and surgical (robust fixation to the iris and long-term biocompatibility in the intraocular environment) aspects, all meeting specifications for future practical implementation of such IOP sensing technology.</description><subject>Animals</subject><subject>Coils</subject><subject>In vivo</subject><subject>Iris</subject><subject>Minimally invasive surgery</subject><subject>Patient monitoring</subject><subject>Robustness</subject><subject>Sensor phenomena and characterization</subject><subject>Testing</subject><subject>Wireless sensor networks</subject><issn>1084-6999</issn><isbn>1424429773</isbn><isbn>9781424429776</isbn><isbn>1424429781</isbn><isbn>9781424429783</isbn><fulltext>true</fulltext><rsrctype>conference_proceeding</rsrctype><creationdate>2009</creationdate><recordtype>conference_proceeding</recordtype><sourceid>6IE</sourceid><sourceid>RIE</sourceid><recordid>eNpFT91KwzAYjajgnHuC3fQFWr_8NcmdUjYtbChUEa9G0n6FSLaOpAN9ewsOPDfn5-IcDiFLCgWlYO63q23z2RQMwBRCg-SluCC3VDAhmFGaXv4bxa_IjIIWeWmMuSGLlL5ggpCca5iRh3p_DPYwWhcwWwf89pPIq8EH7LIPHzFgSll9GKMd2lOwMXuNU3KKmDV4SEO8I9e9DQkXZ56T9_XqrXrONy9PdfW4yT1jMOZWWaYd4900jMxIpVpoe6qFA6k7NC3rTQecOcURpHWOO1NqVMCV6KRVfE6Wf70eEXfH6Pc2_uzO7_kvDltMXw</recordid><startdate>200901</startdate><enddate>200901</enddate><creator>Po-Jui Chen</creator><creator>Saati, S.</creator><creator>Varma, R.</creator><creator>Humayun, M.S.</creator><creator>Yu-Chong Tai</creator><general>IEEE</general><scope>6IE</scope><scope>6IH</scope><scope>CBEJK</scope><scope>RIE</scope><scope>RIO</scope></search><sort><creationdate>200901</creationdate><title>Implantable Flexible-Coiled Wireless Intraocular Pressure Sensor</title><author>Po-Jui Chen ; Saati, S. ; Varma, R. ; Humayun, M.S. ; Yu-Chong Tai</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-i220t-a7a28b23d453e29577c0cf184b058de9c2f9d032b73e05abb3b968e70374d5a73</frbrgroupid><rsrctype>conference_proceedings</rsrctype><prefilter>conference_proceedings</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Animals</topic><topic>Coils</topic><topic>In vivo</topic><topic>Iris</topic><topic>Minimally invasive surgery</topic><topic>Patient monitoring</topic><topic>Robustness</topic><topic>Sensor phenomena and characterization</topic><topic>Testing</topic><topic>Wireless sensor networks</topic><toplevel>online_resources</toplevel><creatorcontrib>Po-Jui Chen</creatorcontrib><creatorcontrib>Saati, S.</creatorcontrib><creatorcontrib>Varma, R.</creatorcontrib><creatorcontrib>Humayun, M.S.</creatorcontrib><creatorcontrib>Yu-Chong Tai</creatorcontrib><collection>IEEE Electronic Library (IEL) Conference Proceedings</collection><collection>IEEE Proceedings Order Plan (POP) 1998-present by volume</collection><collection>IEEE Xplore All Conference Proceedings</collection><collection>IEEE Electronic Library (IEL)</collection><collection>IEEE Proceedings Order Plans (POP) 1998-present</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Po-Jui Chen</au><au>Saati, S.</au><au>Varma, R.</au><au>Humayun, M.S.</au><au>Yu-Chong Tai</au><format>book</format><genre>proceeding</genre><ristype>CONF</ristype><atitle>Implantable Flexible-Coiled Wireless Intraocular Pressure Sensor</atitle><btitle>2009 IEEE 22nd International Conference on Micro Electro Mechanical Systems</btitle><stitle>MEMSYS</stitle><date>2009-01</date><risdate>2009</risdate><spage>244</spage><epage>247</epage><pages>244-247</pages><issn>1084-6999</issn><isbn>1424429773</isbn><isbn>9781424429776</isbn><eisbn>1424429781</eisbn><eisbn>9781424429783</eisbn><abstract>This work presents an implantable wireless passive pressure sensor for long-range continuous intraocular pressure (IOP) monitoring of glaucoma patients. The sensor is microfabricated with use of parylene C (poly-chloro-p-xylylene) to create a flexible coil substrate that can be folded during implantation for suture-less minimally invasive surgery, while stretched back without damage for enhanced inductive sensor-reader coil coupling and the corresponding sensing signal. Extensive device characterizations including on-bench testing and in vivo and ex vivo animal studies verify the device feasibility in both engineering (1 mmHg pressure sensing accuracy and 2 cm sensing distance) and surgical (robust fixation to the iris and long-term biocompatibility in the intraocular environment) aspects, all meeting specifications for future practical implementation of such IOP sensing technology.</abstract><pub>IEEE</pub><doi>10.1109/MEMSYS.2009.4805364</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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language | eng |
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source | IEEE Electronic Library (IEL) Conference Proceedings |
subjects | Animals Coils In vivo Iris Minimally invasive surgery Patient monitoring Robustness Sensor phenomena and characterization Testing Wireless sensor networks |
title | Implantable Flexible-Coiled Wireless Intraocular Pressure Sensor |
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