Automated localization and quantification of protein multiplexes via multispectral fluorescence imaging

We present a new system for automated localization and quantification of the expression of protein biomarkers in immunofluorescence (IF) microscopic images. The system includes a novel method for discriminating the biomarker signal from background, where signal may be the expression of any of the ma...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	Teverovskiy, M., Vengrenyuk, Y., Tabesh, A., Sapir, M., Fogarasi, S., Ho-Yuen Pang, Khan, F.M., Hamann, S., Capodieci, P., Clayton, M., Kim, R., Fernandez, G., Mesa-Tejada, R., Donovan, M.J.
Format:	Tagungsbericht
Sprache:	eng
Schlagworte:	Biomarkers Fluorescence Fluorescence microscopy Image color analysis Image segmentation image thresholding immunofluorescence Laboratories Microscopy Multispectral imaging Pixel Prostate cancer Proteins
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