Design of a High Frequency Array Based Photoacoustic Microscopy System for Micro-Vascular Imaging
The rapidly expanding field of photoacoustic imaging includes a technique called photoacoustic microscopy. Photoacoustic microscopy is a hybrid imaging modality with sub-millimeter resolution that possesses the contrast benefit of optical imaging and the resolution benefit of ultrasonic imaging. Thi...
Gespeichert in:
| Hauptverfasser: | , , , , |
|---|---|
| Format: | Tagungsbericht |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 2178 |
|---|---|
| container_issue | |
| container_start_page | 2175 |
| container_title | |
| container_volume | 2007 |
| creator | Bitton, R. Zemp, R. Yen, J. Wang, L.H. Shung, K.K. |
| description | The rapidly expanding field of photoacoustic imaging includes a technique called photoacoustic microscopy. Photoacoustic microscopy is a hybrid imaging modality with sub-millimeter resolution that possesses the contrast benefit of optical imaging and the resolution benefit of ultrasonic imaging. This technique can be used to image the structure and dynamics of microvessels involved in angiogenesis within biological tissue. In this paper we present results of a new high frequency array based photoacoustic microscopy system (PAM) using an Nd:YLF pumped tunable dye laser, a 30 MHz piezo composite linear array and a custom multi-channel receiver system. Using offline delay and sum beamforming and beamsteering, phantom images were obtained from a 6 mum carbon fiber in water at a depth of 8 mm. The measured axial and lateral spatial resolution of the system was 103 plusmn 5 mum and 45+5 mum, respectively. In vivo B-scans were obtained from vessels within a human hand as well as 3D photoacoustic images of vessels 3 mm below the skin surface in a Sprague Dawley Rat. |
| doi_str_mv | 10.1109/IEMBS.2007.4352754 |
| format | Conference Proceeding |
| fullrecord | <record><control><sourceid>pubmed_6IE</sourceid><recordid>TN_cdi_ieee_primary_4352754</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><ieee_id>4352754</ieee_id><sourcerecordid>18002420</sourcerecordid><originalsourceid>FETCH-LOGICAL-i338t-6de2df4a9039175930818f765a46d9b67c727f840216be34b00071b9da7f53123</originalsourceid><addsrcrecordid>eNpVkNtKw0AURccbttT-gILMD6TO_fLY1lYLLQpV8a1MJpN0pGnqTPKQvzfQKnheDpy12ex9ALjFaIQx0g-L2WqyHhGE5IhRTiRnZ2CopcKMMIakUugc9DHnKmEC84t_TNLLjiHNEqHkZw8MY_xC3VDdYXUNelghRBhBfWAeXfTFHlY5NPDZF1s4D-67cXvbwnEIpoUTE10GX7dVXRlbNbH2Fq68DVW01aGF6zbWroR5FY7X5MNE2-xMgIvSFH5f3ICr3OyiG572ALzPZ2_T52T58rSYjpeJp1TVicgcyXJmdJcSS64pUljlUnDDRKZTIa0kMlcMESxSR1na9ZE41ZmROaeY0AG4P_oemrR02eYQfGlCu_nt2gnujgLvnPvDp-fSH_PCZSU</addsrcrecordid><sourcetype>Index Database</sourcetype><iscdi>true</iscdi><recordtype>conference_proceeding</recordtype></control><display><type>conference_proceeding</type><title>Design of a High Frequency Array Based Photoacoustic Microscopy System for Micro-Vascular Imaging</title><source>IEEE Electronic Library (IEL) Conference Proceedings</source><creator>Bitton, R. ; Zemp, R. ; Yen, J. ; Wang, L.H. ; Shung, K.K.</creator><creatorcontrib>Bitton, R. ; Zemp, R. ; Yen, J. ; Wang, L.H. ; Shung, K.K.</creatorcontrib><description>The rapidly expanding field of photoacoustic imaging includes a technique called photoacoustic microscopy. Photoacoustic microscopy is a hybrid imaging modality with sub-millimeter resolution that possesses the contrast benefit of optical imaging and the resolution benefit of ultrasonic imaging. This technique can be used to image the structure and dynamics of microvessels involved in angiogenesis within biological tissue. In this paper we present results of a new high frequency array based photoacoustic microscopy system (PAM) using an Nd:YLF pumped tunable dye laser, a 30 MHz piezo composite linear array and a custom multi-channel receiver system. Using offline delay and sum beamforming and beamsteering, phantom images were obtained from a 6 mum carbon fiber in water at a depth of 8 mm. The measured axial and lateral spatial resolution of the system was 103 plusmn 5 mum and 45+5 mum, respectively. In vivo B-scans were obtained from vessels within a human hand as well as 3D photoacoustic images of vessels 3 mm below the skin surface in a Sprague Dawley Rat.</description><identifier>ISSN: 1094-687X</identifier><identifier>ISSN: 1557-170X</identifier><identifier>ISBN: 9781424407873</identifier><identifier>ISBN: 1424407877</identifier><identifier>EISSN: 1558-4615</identifier><identifier>EISBN: 9781424407880</identifier><identifier>EISBN: 1424407885</identifier><identifier>DOI: 10.1109/IEMBS.2007.4352754</identifier><identifier>PMID: 18002420</identifier><language>eng</language><publisher>United States: IEEE</publisher><subject>Animals ; Biological tissues ; Carbon - chemistry ; Equipment Design ; Frequency ; Hand - pathology ; High-resolution imaging ; Humans ; Image Enhancement ; Image resolution ; Laser excitation ; Lasers ; Microcirculation - pathology ; Microscopy, Acoustic - instrumentation ; Microscopy, Acoustic - methods ; Models, Statistical ; Optical arrays ; Optical imaging ; Optical microscopy ; Rats ; Rats, Sprague-Dawley ; Skin - pathology ; Tomography, Optical - instrumentation ; Tomography, Optical - methods ; Tunable circuits and devices ; Ultrasonic imaging ; Ultrasonography - instrumentation ; Ultrasonography - methods</subject><ispartof>2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2007, Vol.2007, p.2175-2178</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://ieeexplore.ieee.org/document/4352754$$EHTML$$P50$$Gieee$$H</linktohtml><link.rule.ids>309,310,776,780,785,786,2052,27902,54895</link.rule.ids><linktorsrc>$$Uhttps://ieeexplore.ieee.org/document/4352754$$EView_record_in_IEEE$$FView_record_in_$$GIEEE</linktorsrc><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18002420$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bitton, R.</creatorcontrib><creatorcontrib>Zemp, R.</creatorcontrib><creatorcontrib>Yen, J.</creatorcontrib><creatorcontrib>Wang, L.H.</creatorcontrib><creatorcontrib>Shung, K.K.</creatorcontrib><title>Design of a High Frequency Array Based Photoacoustic Microscopy System for Micro-Vascular Imaging</title><title>2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society</title><addtitle>IEMBS</addtitle><addtitle>Conf Proc IEEE Eng Med Biol Soc</addtitle><description>The rapidly expanding field of photoacoustic imaging includes a technique called photoacoustic microscopy. Photoacoustic microscopy is a hybrid imaging modality with sub-millimeter resolution that possesses the contrast benefit of optical imaging and the resolution benefit of ultrasonic imaging. This technique can be used to image the structure and dynamics of microvessels involved in angiogenesis within biological tissue. In this paper we present results of a new high frequency array based photoacoustic microscopy system (PAM) using an Nd:YLF pumped tunable dye laser, a 30 MHz piezo composite linear array and a custom multi-channel receiver system. Using offline delay and sum beamforming and beamsteering, phantom images were obtained from a 6 mum carbon fiber in water at a depth of 8 mm. The measured axial and lateral spatial resolution of the system was 103 plusmn 5 mum and 45+5 mum, respectively. In vivo B-scans were obtained from vessels within a human hand as well as 3D photoacoustic images of vessels 3 mm below the skin surface in a Sprague Dawley Rat.</description><subject>Animals</subject><subject>Biological tissues</subject><subject>Carbon - chemistry</subject><subject>Equipment Design</subject><subject>Frequency</subject><subject>Hand - pathology</subject><subject>High-resolution imaging</subject><subject>Humans</subject><subject>Image Enhancement</subject><subject>Image resolution</subject><subject>Laser excitation</subject><subject>Lasers</subject><subject>Microcirculation - pathology</subject><subject>Microscopy, Acoustic - instrumentation</subject><subject>Microscopy, Acoustic - methods</subject><subject>Models, Statistical</subject><subject>Optical arrays</subject><subject>Optical imaging</subject><subject>Optical microscopy</subject><subject>Rats</subject><subject>Rats, Sprague-Dawley</subject><subject>Skin - pathology</subject><subject>Tomography, Optical - instrumentation</subject><subject>Tomography, Optical - methods</subject><subject>Tunable circuits and devices</subject><subject>Ultrasonic imaging</subject><subject>Ultrasonography - instrumentation</subject><subject>Ultrasonography - methods</subject><issn>1094-687X</issn><issn>1557-170X</issn><issn>1558-4615</issn><isbn>9781424407873</isbn><isbn>1424407877</isbn><isbn>9781424407880</isbn><isbn>1424407885</isbn><fulltext>true</fulltext><rsrctype>conference_proceeding</rsrctype><creationdate>2007</creationdate><recordtype>conference_proceeding</recordtype><sourceid>6IE</sourceid><sourceid>RIE</sourceid><sourceid>EIF</sourceid><recordid>eNpVkNtKw0AURccbttT-gILMD6TO_fLY1lYLLQpV8a1MJpN0pGnqTPKQvzfQKnheDpy12ex9ALjFaIQx0g-L2WqyHhGE5IhRTiRnZ2CopcKMMIakUugc9DHnKmEC84t_TNLLjiHNEqHkZw8MY_xC3VDdYXUNelghRBhBfWAeXfTFHlY5NPDZF1s4D-67cXvbwnEIpoUTE10GX7dVXRlbNbH2Fq68DVW01aGF6zbWroR5FY7X5MNE2-xMgIvSFH5f3ICr3OyiG572ALzPZ2_T52T58rSYjpeJp1TVicgcyXJmdJcSS64pUljlUnDDRKZTIa0kMlcMESxSR1na9ZE41ZmROaeY0AG4P_oemrR02eYQfGlCu_nt2gnujgLvnPvDp-fSH_PCZSU</recordid><startdate>20070101</startdate><enddate>20070101</enddate><creator>Bitton, R.</creator><creator>Zemp, R.</creator><creator>Yen, J.</creator><creator>Wang, L.H.</creator><creator>Shung, K.K.</creator><general>IEEE</general><scope>6IE</scope><scope>6IH</scope><scope>CBEJK</scope><scope>RIE</scope><scope>RIO</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope></search><sort><creationdate>20070101</creationdate><title>Design of a High Frequency Array Based Photoacoustic Microscopy System for Micro-Vascular Imaging</title><author>Bitton, R. ; Zemp, R. ; Yen, J. ; Wang, L.H. ; Shung, K.K.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-i338t-6de2df4a9039175930818f765a46d9b67c727f840216be34b00071b9da7f53123</frbrgroupid><rsrctype>conference_proceedings</rsrctype><prefilter>conference_proceedings</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Animals</topic><topic>Biological tissues</topic><topic>Carbon - chemistry</topic><topic>Equipment Design</topic><topic>Frequency</topic><topic>Hand - pathology</topic><topic>High-resolution imaging</topic><topic>Humans</topic><topic>Image Enhancement</topic><topic>Image resolution</topic><topic>Laser excitation</topic><topic>Lasers</topic><topic>Microcirculation - pathology</topic><topic>Microscopy, Acoustic - instrumentation</topic><topic>Microscopy, Acoustic - methods</topic><topic>Models, Statistical</topic><topic>Optical arrays</topic><topic>Optical imaging</topic><topic>Optical microscopy</topic><topic>Rats</topic><topic>Rats, Sprague-Dawley</topic><topic>Skin - pathology</topic><topic>Tomography, Optical - instrumentation</topic><topic>Tomography, Optical - methods</topic><topic>Tunable circuits and devices</topic><topic>Ultrasonic imaging</topic><topic>Ultrasonography - instrumentation</topic><topic>Ultrasonography - methods</topic><toplevel>online_resources</toplevel><creatorcontrib>Bitton, R.</creatorcontrib><creatorcontrib>Zemp, R.</creatorcontrib><creatorcontrib>Yen, J.</creatorcontrib><creatorcontrib>Wang, L.H.</creatorcontrib><creatorcontrib>Shung, K.K.</creatorcontrib><collection>IEEE Electronic Library (IEL) Conference Proceedings</collection><collection>IEEE Proceedings Order Plan (POP) 1998-present by volume</collection><collection>IEEE Xplore All Conference Proceedings</collection><collection>IEEE Electronic Library (IEL)</collection><collection>IEEE Proceedings Order Plans (POP) 1998-present</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Bitton, R.</au><au>Zemp, R.</au><au>Yen, J.</au><au>Wang, L.H.</au><au>Shung, K.K.</au><format>book</format><genre>proceeding</genre><ristype>CONF</ristype><atitle>Design of a High Frequency Array Based Photoacoustic Microscopy System for Micro-Vascular Imaging</atitle><btitle>2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society</btitle><stitle>IEMBS</stitle><addtitle>Conf Proc IEEE Eng Med Biol Soc</addtitle><date>2007-01-01</date><risdate>2007</risdate><volume>2007</volume><spage>2175</spage><epage>2178</epage><pages>2175-2178</pages><issn>1094-687X</issn><issn>1557-170X</issn><eissn>1558-4615</eissn><isbn>9781424407873</isbn><isbn>1424407877</isbn><eisbn>9781424407880</eisbn><eisbn>1424407885</eisbn><abstract>The rapidly expanding field of photoacoustic imaging includes a technique called photoacoustic microscopy. Photoacoustic microscopy is a hybrid imaging modality with sub-millimeter resolution that possesses the contrast benefit of optical imaging and the resolution benefit of ultrasonic imaging. This technique can be used to image the structure and dynamics of microvessels involved in angiogenesis within biological tissue. In this paper we present results of a new high frequency array based photoacoustic microscopy system (PAM) using an Nd:YLF pumped tunable dye laser, a 30 MHz piezo composite linear array and a custom multi-channel receiver system. Using offline delay and sum beamforming and beamsteering, phantom images were obtained from a 6 mum carbon fiber in water at a depth of 8 mm. The measured axial and lateral spatial resolution of the system was 103 plusmn 5 mum and 45+5 mum, respectively. In vivo B-scans were obtained from vessels within a human hand as well as 3D photoacoustic images of vessels 3 mm below the skin surface in a Sprague Dawley Rat.</abstract><cop>United States</cop><pub>IEEE</pub><pmid>18002420</pmid><doi>10.1109/IEMBS.2007.4352754</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | ISSN: 1094-687X |
| ispartof | 2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2007, Vol.2007, p.2175-2178 |
| issn | 1094-687X 1557-170X 1558-4615 |
| language | eng |
| recordid | cdi_ieee_primary_4352754 |
| source | IEEE Electronic Library (IEL) Conference Proceedings |
| subjects | Animals Biological tissues Carbon - chemistry Equipment Design Frequency Hand - pathology High-resolution imaging Humans Image Enhancement Image resolution Laser excitation Lasers Microcirculation - pathology Microscopy, Acoustic - instrumentation Microscopy, Acoustic - methods Models, Statistical Optical arrays Optical imaging Optical microscopy Rats Rats, Sprague-Dawley Skin - pathology Tomography, Optical - instrumentation Tomography, Optical - methods Tunable circuits and devices Ultrasonic imaging Ultrasonography - instrumentation Ultrasonography - methods |
| title | Design of a High Frequency Array Based Photoacoustic Microscopy System for Micro-Vascular Imaging |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-12T20%3A17%3A34IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-pubmed_6IE&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=proceeding&rft.atitle=Design%20of%20a%20High%20Frequency%20Array%20Based%20Photoacoustic%20Microscopy%20System%20for%20Micro-Vascular%20Imaging&rft.btitle=2007%2029th%20Annual%20International%20Conference%20of%20the%20IEEE%20Engineering%20in%20Medicine%20and%20Biology%20Society&rft.au=Bitton,%20R.&rft.date=2007-01-01&rft.volume=2007&rft.spage=2175&rft.epage=2178&rft.pages=2175-2178&rft.issn=1094-687X&rft.eissn=1558-4615&rft.isbn=9781424407873&rft.isbn_list=1424407877&rft_id=info:doi/10.1109/IEMBS.2007.4352754&rft_dat=%3Cpubmed_6IE%3E18002420%3C/pubmed_6IE%3E%3Curl%3E%3C/url%3E&rft.eisbn=9781424407880&rft.eisbn_list=1424407885&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/18002420&rft_ieee_id=4352754&rfr_iscdi=true |