System-on-Chip Circuit Architecture for Eliminating Interferents in Surface Plasmon Resonance Sensing Systems
This paper presents a system-on-chip circuit architecture that enables the extraction of concentration information directly from a surface plasmon resonance (SPR) probe, independent of ambient fluctuations in the reference medium, temperature, and background light. Compensation for these baseline (b...
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| Veröffentlicht in: | IEEE sensors journal 2007-10, Vol.7 (10), p.1400-1412 |
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| container_title | IEEE sensors journal |
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| creator | Johnston, M.M.W. Hansen, L.E. Wilson, D.M. Booksh, K.S. |
| description | This paper presents a system-on-chip circuit architecture that enables the extraction of concentration information directly from a surface plasmon resonance (SPR) probe, independent of ambient fluctuations in the reference medium, temperature, and background light. Compensation for these baseline (bulk) interferences is embedded into the baseline integration state of the photodetectors in the optical path, creating a ldquoflat linerdquo for the baseline [no analyte present/bulk refractive index (RI)] condition and the characteristic SPR dips for the measurement (analyte present) condition. A resolution of 2 times 10 -4 RI units is possible with this system, comparable to the 5 times 10 -4 RI unit resolution of conventional signal processing (software-based) approaches to processing the same data using a similar framework. This approach demonstrates experimentally the capability of the dip-based SPR probe in a portable footprint for detecting RI at resolution levels suitable for practical applications of these probes to field environments. |
| doi_str_mv | 10.1109/JSEN.2007.904234 |
| format | Article |
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Compensation for these baseline (bulk) interferences is embedded into the baseline integration state of the photodetectors in the optical path, creating a ldquoflat linerdquo for the baseline [no analyte present/bulk refractive index (RI)] condition and the characteristic SPR dips for the measurement (analyte present) condition. A resolution of 2 times 10 -4 RI units is possible with this system, comparable to the 5 times 10 -4 RI unit resolution of conventional signal processing (software-based) approaches to processing the same data using a similar framework. This approach demonstrates experimentally the capability of the dip-based SPR probe in a portable footprint for detecting RI at resolution levels suitable for practical applications of these probes to field environments.</description><identifier>ISSN: 1530-437X</identifier><identifier>EISSN: 1558-1748</identifier><identifier>DOI: 10.1109/JSEN.2007.904234</identifier><identifier>CODEN: ISJEAZ</identifier><language>eng</language><publisher>New York: IEEE</publisher><subject>Analog integrated circuits ; analog VLSI ; Architecture ; chemical sensors ; Circuits ; Data mining ; Dipping ; Fluctuation ; Fluctuations ; Footprints ; Interference ; optical computation ; optical sensors ; Plasmons ; Probes ; Refractive index ; Resonance ; RLC circuits ; Signal resolution ; surface plasmon resonance (SPR) ; System on chip ; System-on-a-chip ; Temperature sensors</subject><ispartof>IEEE sensors journal, 2007-10, Vol.7 (10), p.1400-1412</ispartof><rights>Copyright The Institute of Electrical and Electronics Engineers, Inc. (IEEE) 2007</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c385t-205402903cd264b4a28b9bd903870c7b45bc3cd12a2047c94d9ac0af2033b2433</citedby><cites>FETCH-LOGICAL-c385t-205402903cd264b4a28b9bd903870c7b45bc3cd12a2047c94d9ac0af2033b2433</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://ieeexplore.ieee.org/document/4289823$$EHTML$$P50$$Gieee$$H</linktohtml><link.rule.ids>314,776,780,792,27901,27902,54733</link.rule.ids><linktorsrc>$$Uhttps://ieeexplore.ieee.org/document/4289823$$EView_record_in_IEEE$$FView_record_in_$$GIEEE</linktorsrc></links><search><creatorcontrib>Johnston, M.M.W.</creatorcontrib><creatorcontrib>Hansen, L.E.</creatorcontrib><creatorcontrib>Wilson, D.M.</creatorcontrib><creatorcontrib>Booksh, K.S.</creatorcontrib><title>System-on-Chip Circuit Architecture for Eliminating Interferents in Surface Plasmon Resonance Sensing Systems</title><title>IEEE sensors journal</title><addtitle>JSEN</addtitle><description>This paper presents a system-on-chip circuit architecture that enables the extraction of concentration information directly from a surface plasmon resonance (SPR) probe, independent of ambient fluctuations in the reference medium, temperature, and background light. Compensation for these baseline (bulk) interferences is embedded into the baseline integration state of the photodetectors in the optical path, creating a ldquoflat linerdquo for the baseline [no analyte present/bulk refractive index (RI)] condition and the characteristic SPR dips for the measurement (analyte present) condition. A resolution of 2 times 10 -4 RI units is possible with this system, comparable to the 5 times 10 -4 RI unit resolution of conventional signal processing (software-based) approaches to processing the same data using a similar framework. This approach demonstrates experimentally the capability of the dip-based SPR probe in a portable footprint for detecting RI at resolution levels suitable for practical applications of these probes to field environments.</description><subject>Analog integrated circuits</subject><subject>analog VLSI</subject><subject>Architecture</subject><subject>chemical sensors</subject><subject>Circuits</subject><subject>Data mining</subject><subject>Dipping</subject><subject>Fluctuation</subject><subject>Fluctuations</subject><subject>Footprints</subject><subject>Interference</subject><subject>optical computation</subject><subject>optical sensors</subject><subject>Plasmons</subject><subject>Probes</subject><subject>Refractive index</subject><subject>Resonance</subject><subject>RLC circuits</subject><subject>Signal resolution</subject><subject>surface plasmon resonance (SPR)</subject><subject>System on chip</subject><subject>System-on-a-chip</subject><subject>Temperature sensors</subject><issn>1530-437X</issn><issn>1558-1748</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>RIE</sourceid><recordid>eNqFkT1v3DAMho2gBZKm2QNkETK0k6_Uh0_SGByubYogDXIp0E2QdXSjwJYvkjzk31eGiw4dmokE-bwkyLeqzimsKAX96dtue7tiAHKlQTAujqoT2jSqplKoN3POoRZc_jyu3qX0BEC1bORJNexeUsahHkO9efQHsvHRTT6Tq-gefUaXp4ikGyPZ9n7wwWYffpHrkDF2GDHkRHwguyl21iG5620axkDuMY3BhlLZYUizYtmS3ldvO9snPPsTT6sfn7cPm6_1zfcv15urm9px1eSaQSOAaeBuz9aiFZapVrf7UlASnGxF07rSo8wyENJpsdfWge0YcN4ywflp9XGZe4jj84Qpm8Enh31vA45TMmXSWjRMwqukUlpQrbQs5If_klyIdXl2U8DLf8CncYqh3GtU2apB0XWBYIFcHFOK2JlD9IONL4aCmQ01s6FmNtQshhbJxSLxiPgXF0xpxTj_DbYdm-8</recordid><startdate>200710</startdate><enddate>200710</enddate><creator>Johnston, M.M.W.</creator><creator>Hansen, L.E.</creator><creator>Wilson, D.M.</creator><creator>Booksh, K.S.</creator><general>IEEE</general><general>The Institute of Electrical and Electronics Engineers, Inc. (IEEE)</general><scope>97E</scope><scope>RIA</scope><scope>RIE</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7SP</scope><scope>7U5</scope><scope>8FD</scope><scope>L7M</scope><scope>F28</scope><scope>FR3</scope></search><sort><creationdate>200710</creationdate><title>System-on-Chip Circuit Architecture for Eliminating Interferents in Surface Plasmon Resonance Sensing Systems</title><author>Johnston, M.M.W. ; Hansen, L.E. ; Wilson, D.M. ; Booksh, K.S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c385t-205402903cd264b4a28b9bd903870c7b45bc3cd12a2047c94d9ac0af2033b2433</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Analog integrated circuits</topic><topic>analog VLSI</topic><topic>Architecture</topic><topic>chemical sensors</topic><topic>Circuits</topic><topic>Data mining</topic><topic>Dipping</topic><topic>Fluctuation</topic><topic>Fluctuations</topic><topic>Footprints</topic><topic>Interference</topic><topic>optical computation</topic><topic>optical sensors</topic><topic>Plasmons</topic><topic>Probes</topic><topic>Refractive index</topic><topic>Resonance</topic><topic>RLC circuits</topic><topic>Signal resolution</topic><topic>surface plasmon resonance (SPR)</topic><topic>System on chip</topic><topic>System-on-a-chip</topic><topic>Temperature sensors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Johnston, M.M.W.</creatorcontrib><creatorcontrib>Hansen, L.E.</creatorcontrib><creatorcontrib>Wilson, D.M.</creatorcontrib><creatorcontrib>Booksh, K.S.</creatorcontrib><collection>IEEE All-Society Periodicals Package (ASPP) 2005-present</collection><collection>IEEE All-Society Periodicals Package (ASPP) 1998-Present</collection><collection>IEEE Electronic Library (IEL)</collection><collection>CrossRef</collection><collection>Electronics & Communications Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Technology Research Database</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>ANTE: Abstracts in New Technology & Engineering</collection><collection>Engineering Research Database</collection><jtitle>IEEE sensors journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Johnston, M.M.W.</au><au>Hansen, L.E.</au><au>Wilson, D.M.</au><au>Booksh, K.S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>System-on-Chip Circuit Architecture for Eliminating Interferents in Surface Plasmon Resonance Sensing Systems</atitle><jtitle>IEEE sensors journal</jtitle><stitle>JSEN</stitle><date>2007-10</date><risdate>2007</risdate><volume>7</volume><issue>10</issue><spage>1400</spage><epage>1412</epage><pages>1400-1412</pages><issn>1530-437X</issn><eissn>1558-1748</eissn><coden>ISJEAZ</coden><abstract>This paper presents a system-on-chip circuit architecture that enables the extraction of concentration information directly from a surface plasmon resonance (SPR) probe, independent of ambient fluctuations in the reference medium, temperature, and background light. Compensation for these baseline (bulk) interferences is embedded into the baseline integration state of the photodetectors in the optical path, creating a ldquoflat linerdquo for the baseline [no analyte present/bulk refractive index (RI)] condition and the characteristic SPR dips for the measurement (analyte present) condition. A resolution of 2 times 10 -4 RI units is possible with this system, comparable to the 5 times 10 -4 RI unit resolution of conventional signal processing (software-based) approaches to processing the same data using a similar framework. This approach demonstrates experimentally the capability of the dip-based SPR probe in a portable footprint for detecting RI at resolution levels suitable for practical applications of these probes to field environments.</abstract><cop>New York</cop><pub>IEEE</pub><doi>10.1109/JSEN.2007.904234</doi><tpages>13</tpages></addata></record> |
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| subjects | Analog integrated circuits analog VLSI Architecture chemical sensors Circuits Data mining Dipping Fluctuation Fluctuations Footprints Interference optical computation optical sensors Plasmons Probes Refractive index Resonance RLC circuits Signal resolution surface plasmon resonance (SPR) System on chip System-on-a-chip Temperature sensors |
| title | System-on-Chip Circuit Architecture for Eliminating Interferents in Surface Plasmon Resonance Sensing Systems |
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