Unexcitable zones as a source of spiral waves initiation and cardiac arrhythmias

The initiation of a 2-D spiral wave rotation around a periodic lattice of unexcitable zones (obstacles) is studied numerically by the finite-difference method. The lattice consists of thin asymmetrical filaments formed by unexcitable (diseased) portions of heart tissue. A spiral-like wave rotation o...

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Hauptverfasser: Starobin, J.M., Zilberter, Y.I., Starmer, C.F.
Format: Tagungsbericht
Sprache:eng
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Zusammenfassung:The initiation of a 2-D spiral wave rotation around a periodic lattice of unexcitable zones (obstacles) is studied numerically by the finite-difference method. The lattice consists of thin asymmetrical filaments formed by unexcitable (diseased) portions of heart tissue. A spiral-like wave rotation originates from the incident wavefront break which occurred at the obstacles. The conditions are found when a rotation frequency of the broken wavefront fragments is several times greater than the frequency of a normal heart rhythm.< >
DOI:10.1109/IEMBS.1994.412162