An autofluorescence imaging method for detecting neoplastic growths in vivo

To evaluate the capabilities of a calibrated autofluorescence imaging method for detecting neoplastic lesions, an imaging system that records autofluorescence images calibrated by the cross-polarized reflection images from excitation was instrumented. Cervical tissue was selected as the living tissu...

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Hauptverfasser: Wu, T.T., Cheung, T.H., Yue Wen, Qu, J.Y.
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Yue Wen
Qu, J.Y.
description To evaluate the capabilities of a calibrated autofluorescence imaging method for detecting neoplastic lesions, an imaging system that records autofluorescence images calibrated by the cross-polarized reflection images from excitation was instrumented. Cervical tissue was selected as the living tissue material. Sixteen human subjects were examined in vivo with the imaging system before the loop electrosurgical excision procedure. It was found that neoplastic lesions can be differentiated from surrounding normal tissue based on the contrast in the calibrated autofluorescence signals, which from neoplastic lesions were generally lower than that from normal cervical tissue.
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subjects Adaptive optics
Fluorescence
In vivo
Lesions
Lighting
Optical filters
Optical imaging
Optical polarization
Optical reflection
Optical sensors
title An autofluorescence imaging method for detecting neoplastic growths in vivo
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