The effects of epithelial surface topography on cell stresses during airway reopening
A collapsed pulmonary system is one whose airways are blocked by a thin liquid film that obstructs airflow. A bubble of air must peel apart these airways' walls in order to reopen them. This introduces large stresses on the pulmonary epithelial cells of a magnitude that could alter their biolog...
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creator | Jacob, A.M. Gaver, D.P. |
description | A collapsed pulmonary system is one whose airways are blocked by a thin liquid film that obstructs airflow. A bubble of air must peel apart these airways' walls in order to reopen them. This introduces large stresses on the pulmonary epithelial cells of a magnitude that could alter their biological functioning. We present a computational model whose goal it is to locally quantify the stresses acting on these cells. |
doi_str_mv | 10.1109/IEMBS.2002.1106496 |
format | Conference Proceeding |
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A bubble of air must peel apart these airways' walls in order to reopen them. This introduces large stresses on the pulmonary epithelial cells of a magnitude that could alter their biological functioning. We present a computational model whose goal it is to locally quantify the stresses acting on these cells.</description><identifier>ISSN: 1094-687X</identifier><identifier>ISBN: 0780376129</identifier><identifier>ISBN: 9780780376120</identifier><identifier>EISSN: 1558-4615</identifier><identifier>DOI: 10.1109/IEMBS.2002.1106496</identifier><language>eng</language><publisher>IEEE</publisher><subject>Biological system modeling ; Biology computing ; Biomedical engineering ; Cells (biology) ; Computational modeling ; Jacobian matrices ; Stress ; Surface tension ; Surface topography ; Ventilation</subject><ispartof>Proceedings of the Second Joint 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society] [Engineering in Medicine and Biology, 2002, Vol.2, p.1483-1484 vol.2</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://ieeexplore.ieee.org/document/1106496$$EHTML$$P50$$Gieee$$H</linktohtml><link.rule.ids>309,310,780,784,789,790,2058,4050,4051,27925,54920</link.rule.ids><linktorsrc>$$Uhttps://ieeexplore.ieee.org/document/1106496$$EView_record_in_IEEE$$FView_record_in_$$GIEEE</linktorsrc></links><search><creatorcontrib>Jacob, A.M.</creatorcontrib><creatorcontrib>Gaver, D.P.</creatorcontrib><title>The effects of epithelial surface topography on cell stresses during airway reopening</title><title>Proceedings of the Second Joint 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society] [Engineering in Medicine and Biology</title><addtitle>IEMBS</addtitle><description>A collapsed pulmonary system is one whose airways are blocked by a thin liquid film that obstructs airflow. A bubble of air must peel apart these airways' walls in order to reopen them. This introduces large stresses on the pulmonary epithelial cells of a magnitude that could alter their biological functioning. 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A bubble of air must peel apart these airways' walls in order to reopen them. This introduces large stresses on the pulmonary epithelial cells of a magnitude that could alter their biological functioning. We present a computational model whose goal it is to locally quantify the stresses acting on these cells.</abstract><pub>IEEE</pub><doi>10.1109/IEMBS.2002.1106496</doi></addata></record> |
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ispartof | Proceedings of the Second Joint 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society] [Engineering in Medicine and Biology, 2002, Vol.2, p.1483-1484 vol.2 |
issn | 1094-687X 1558-4615 |
language | eng |
recordid | cdi_ieee_primary_1106496 |
source | IEEE Electronic Library (IEL) Conference Proceedings |
subjects | Biological system modeling Biology computing Biomedical engineering Cells (biology) Computational modeling Jacobian matrices Stress Surface tension Surface topography Ventilation |
title | The effects of epithelial surface topography on cell stresses during airway reopening |
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