The effects of epithelial surface topography on cell stresses during airway reopening

A collapsed pulmonary system is one whose airways are blocked by a thin liquid film that obstructs airflow. A bubble of air must peel apart these airways' walls in order to reopen them. This introduces large stresses on the pulmonary epithelial cells of a magnitude that could alter their biolog...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Jacob, A.M., Gaver, D.P.
Format: Tagungsbericht
Sprache:eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 1484 vol.2
container_issue
container_start_page 1483
container_title
container_volume 2
creator Jacob, A.M.
Gaver, D.P.
description A collapsed pulmonary system is one whose airways are blocked by a thin liquid film that obstructs airflow. A bubble of air must peel apart these airways' walls in order to reopen them. This introduces large stresses on the pulmonary epithelial cells of a magnitude that could alter their biological functioning. We present a computational model whose goal it is to locally quantify the stresses acting on these cells.
doi_str_mv 10.1109/IEMBS.2002.1106496
format Conference Proceeding
fullrecord <record><control><sourceid>ieee_6IE</sourceid><recordid>TN_cdi_ieee_primary_1106496</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><ieee_id>1106496</ieee_id><sourcerecordid>1106496</sourcerecordid><originalsourceid>FETCH-ieee_primary_11064963</originalsourceid><addsrcrecordid>eNp9js2KwjAUhYM_oKO-gG7uC9RJ2jRttg6KLlyNA-4k1Js2UpuQVKRvPxVcezaH832bQ8iS0TVjVH4ftsfN7zqmNH5twaUYkClL0zzigqVD8kWznCaZYLEc9YJKHok8O0_IIoQb7cNTxrmckr9ThYBaY9EGsBrQmbbC2qgawsNrVSC01tnSK1d1YBsosO5V6zEEDHB9eNOUoIx_qg48WodND-ZkrFUdcPHuGVnttqeffWQQ8eK8uSvfXd7Pk8_2H0vPRVs</addsrcrecordid><sourcetype>Publisher</sourcetype><iscdi>true</iscdi><recordtype>conference_proceeding</recordtype></control><display><type>conference_proceeding</type><title>The effects of epithelial surface topography on cell stresses during airway reopening</title><source>IEEE Electronic Library (IEL) Conference Proceedings</source><creator>Jacob, A.M. ; Gaver, D.P.</creator><creatorcontrib>Jacob, A.M. ; Gaver, D.P.</creatorcontrib><description>A collapsed pulmonary system is one whose airways are blocked by a thin liquid film that obstructs airflow. A bubble of air must peel apart these airways' walls in order to reopen them. This introduces large stresses on the pulmonary epithelial cells of a magnitude that could alter their biological functioning. We present a computational model whose goal it is to locally quantify the stresses acting on these cells.</description><identifier>ISSN: 1094-687X</identifier><identifier>ISBN: 0780376129</identifier><identifier>ISBN: 9780780376120</identifier><identifier>EISSN: 1558-4615</identifier><identifier>DOI: 10.1109/IEMBS.2002.1106496</identifier><language>eng</language><publisher>IEEE</publisher><subject>Biological system modeling ; Biology computing ; Biomedical engineering ; Cells (biology) ; Computational modeling ; Jacobian matrices ; Stress ; Surface tension ; Surface topography ; Ventilation</subject><ispartof>Proceedings of the Second Joint 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society] [Engineering in Medicine and Biology, 2002, Vol.2, p.1483-1484 vol.2</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://ieeexplore.ieee.org/document/1106496$$EHTML$$P50$$Gieee$$H</linktohtml><link.rule.ids>309,310,780,784,789,790,2058,4050,4051,27925,54920</link.rule.ids><linktorsrc>$$Uhttps://ieeexplore.ieee.org/document/1106496$$EView_record_in_IEEE$$FView_record_in_$$GIEEE</linktorsrc></links><search><creatorcontrib>Jacob, A.M.</creatorcontrib><creatorcontrib>Gaver, D.P.</creatorcontrib><title>The effects of epithelial surface topography on cell stresses during airway reopening</title><title>Proceedings of the Second Joint 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society] [Engineering in Medicine and Biology</title><addtitle>IEMBS</addtitle><description>A collapsed pulmonary system is one whose airways are blocked by a thin liquid film that obstructs airflow. A bubble of air must peel apart these airways' walls in order to reopen them. This introduces large stresses on the pulmonary epithelial cells of a magnitude that could alter their biological functioning. We present a computational model whose goal it is to locally quantify the stresses acting on these cells.</description><subject>Biological system modeling</subject><subject>Biology computing</subject><subject>Biomedical engineering</subject><subject>Cells (biology)</subject><subject>Computational modeling</subject><subject>Jacobian matrices</subject><subject>Stress</subject><subject>Surface tension</subject><subject>Surface topography</subject><subject>Ventilation</subject><issn>1094-687X</issn><issn>1558-4615</issn><isbn>0780376129</isbn><isbn>9780780376120</isbn><fulltext>true</fulltext><rsrctype>conference_proceeding</rsrctype><creationdate>2002</creationdate><recordtype>conference_proceeding</recordtype><sourceid>6IE</sourceid><sourceid>RIE</sourceid><recordid>eNp9js2KwjAUhYM_oKO-gG7uC9RJ2jRttg6KLlyNA-4k1Js2UpuQVKRvPxVcezaH832bQ8iS0TVjVH4ftsfN7zqmNH5twaUYkClL0zzigqVD8kWznCaZYLEc9YJKHok8O0_IIoQb7cNTxrmckr9ThYBaY9EGsBrQmbbC2qgawsNrVSC01tnSK1d1YBsosO5V6zEEDHB9eNOUoIx_qg48WodND-ZkrFUdcPHuGVnttqeffWQQ8eK8uSvfXd7Pk8_2H0vPRVs</recordid><startdate>2002</startdate><enddate>2002</enddate><creator>Jacob, A.M.</creator><creator>Gaver, D.P.</creator><general>IEEE</general><scope>6IE</scope><scope>6IH</scope><scope>CBEJK</scope><scope>RIE</scope><scope>RIO</scope></search><sort><creationdate>2002</creationdate><title>The effects of epithelial surface topography on cell stresses during airway reopening</title><author>Jacob, A.M. ; Gaver, D.P.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-ieee_primary_11064963</frbrgroupid><rsrctype>conference_proceedings</rsrctype><prefilter>conference_proceedings</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Biological system modeling</topic><topic>Biology computing</topic><topic>Biomedical engineering</topic><topic>Cells (biology)</topic><topic>Computational modeling</topic><topic>Jacobian matrices</topic><topic>Stress</topic><topic>Surface tension</topic><topic>Surface topography</topic><topic>Ventilation</topic><toplevel>online_resources</toplevel><creatorcontrib>Jacob, A.M.</creatorcontrib><creatorcontrib>Gaver, D.P.</creatorcontrib><collection>IEEE Electronic Library (IEL) Conference Proceedings</collection><collection>IEEE Proceedings Order Plan (POP) 1998-present by volume</collection><collection>IEEE Xplore All Conference Proceedings</collection><collection>IEEE Electronic Library (IEL)</collection><collection>IEEE Proceedings Order Plans (POP) 1998-present</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Jacob, A.M.</au><au>Gaver, D.P.</au><format>book</format><genre>proceeding</genre><ristype>CONF</ristype><atitle>The effects of epithelial surface topography on cell stresses during airway reopening</atitle><btitle>Proceedings of the Second Joint 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society] [Engineering in Medicine and Biology</btitle><stitle>IEMBS</stitle><date>2002</date><risdate>2002</risdate><volume>2</volume><spage>1483</spage><epage>1484 vol.2</epage><pages>1483-1484 vol.2</pages><issn>1094-687X</issn><eissn>1558-4615</eissn><isbn>0780376129</isbn><isbn>9780780376120</isbn><abstract>A collapsed pulmonary system is one whose airways are blocked by a thin liquid film that obstructs airflow. A bubble of air must peel apart these airways' walls in order to reopen them. This introduces large stresses on the pulmonary epithelial cells of a magnitude that could alter their biological functioning. We present a computational model whose goal it is to locally quantify the stresses acting on these cells.</abstract><pub>IEEE</pub><doi>10.1109/IEMBS.2002.1106496</doi></addata></record>
fulltext fulltext_linktorsrc
identifier ISSN: 1094-687X
ispartof Proceedings of the Second Joint 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society] [Engineering in Medicine and Biology, 2002, Vol.2, p.1483-1484 vol.2
issn 1094-687X
1558-4615
language eng
recordid cdi_ieee_primary_1106496
source IEEE Electronic Library (IEL) Conference Proceedings
subjects Biological system modeling
Biology computing
Biomedical engineering
Cells (biology)
Computational modeling
Jacobian matrices
Stress
Surface tension
Surface topography
Ventilation
title The effects of epithelial surface topography on cell stresses during airway reopening
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-05T08%3A42%3A01IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-ieee_6IE&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=proceeding&rft.atitle=The%20effects%20of%20epithelial%20surface%20topography%20on%20cell%20stresses%20during%20airway%20reopening&rft.btitle=Proceedings%20of%20the%20Second%20Joint%2024th%20Annual%20Conference%20and%20the%20Annual%20Fall%20Meeting%20of%20the%20Biomedical%20Engineering%20Society%5D%20%5BEngineering%20in%20Medicine%20and%20Biology&rft.au=Jacob,%20A.M.&rft.date=2002&rft.volume=2&rft.spage=1483&rft.epage=1484%20vol.2&rft.pages=1483-1484%20vol.2&rft.issn=1094-687X&rft.eissn=1558-4615&rft.isbn=0780376129&rft.isbn_list=9780780376120&rft_id=info:doi/10.1109/IEMBS.2002.1106496&rft_dat=%3Cieee_6IE%3E1106496%3C/ieee_6IE%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rft_ieee_id=1106496&rfr_iscdi=true