GNNGO3D: Protein Function Prediction Based on 3D Structure and Functional Hierarchy Learning

Protein sequences accumulate in large quantities, and the traditional method of annotating protein function by experiment has been unable to bridge the gap between annotated proteins and unannotated proteins. Machine learning-based protein function prediction is an effective approach to solve this p...

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Veröffentlicht in:	IEEE transactions on knowledge and data engineering 2024-08, Vol.36 (8), p.3867-3878
Hauptverfasser:	Zhang, Liyuan, Jiang, Yongquan, Yang, Yan
Format:	Artikel
Sprache:	eng
Schlagworte:	Convolutional neural networks Feature extraction Functionals gene ontology Graph neural networks language model Machine learning Ontologies protein function prediction Protein sequence Proteins Sequences Task analysis Three-dimensional displays
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