Quantitative ischemia detection during cardiac MR stress testing
Because ECG alterations due to ischemia cannot be reliably detected in the high-field MRI environment, detection of wall motion abnormalities are often the only method to ensure patient safety. In this study, we investigate the use of real-time Harmonic Phase (HARP) MRI for the quantitative, operato...
Gespeichert in:
| Hauptverfasser: | , , , , , , |
|---|---|
| Format: | Tagungsbericht |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 2601 vol.3 |
|---|---|
| container_issue | |
| container_start_page | 2598 |
| container_title | |
| container_volume | 3 |
| creator | Kraitchman, D.L. Sampath, S. Derbyshire, J.A. Bluemke, D.A. Gerber, B.L. Prince, J.L. Osman, N.F. |
| description | Because ECG alterations due to ischemia cannot be reliably detected in the high-field MRI environment, detection of wall motion abnormalities are often the only method to ensure patient safety. In this study, we investigate the use of real-time Harmonic Phase (HARP) MRI for the quantitative, operator-independent detection of the onset of ischemia during acute coronary occlusion. Six mongrel dogs underwent acute coronary artery ischemia of 2 minutes' duration while continuous HARP MR images were acquired followed by 5 minutes of reperfusion. During a second ischemic episode, conventional cine wall motion images were acquired. The time from occlusion to the detection of ischemia by each MR technique, as well as ECG ischemic alterations, was determined. In 5 of 6 animals, the onset of ischemia was detected significantly earlier by HARP than by cine MRI (11 /spl plusmn/ 5 s HARP vs. 34 /spl plusmn/ 14.8 s cine, P |
| doi_str_mv | 10.1109/IEMBS.2001.1017313 |
| format | Conference Proceeding |
| fullrecord | <record><control><sourceid>ieee_6IE</sourceid><recordid>TN_cdi_ieee_primary_1017313</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><ieee_id>1017313</ieee_id><sourcerecordid>1017313</sourcerecordid><originalsourceid>FETCH-ieee_primary_10173133</originalsourceid><addsrcrecordid>eNp9zjsLwjAUBeDgAyzaP6BL_kBrbtNXNlEUHRx8DG4S2qtesVWSVPDf28HZw4EzfMthbAwiBBBqullu54cwEgJCEJBJkB3mQZLkQZxC0mW-ynLRVmYRQNJrTag4SPPsNGC-tXfRRqpYqshjs12ja0dOO3ojJ1vcsCLNS3RYOHrWvGwM1VdeaFOSLvh2z60zaC13aF0rI9a_6IdF_7dDNlktj4t1QIh4fhmqtPmcfz_lf_0C6bs92A</addsrcrecordid><sourcetype>Publisher</sourcetype><iscdi>true</iscdi><recordtype>conference_proceeding</recordtype></control><display><type>conference_proceeding</type><title>Quantitative ischemia detection during cardiac MR stress testing</title><source>IEEE Electronic Library (IEL) Conference Proceedings</source><creator>Kraitchman, D.L. ; Sampath, S. ; Derbyshire, J.A. ; Bluemke, D.A. ; Gerber, B.L. ; Prince, J.L. ; Osman, N.F.</creator><creatorcontrib>Kraitchman, D.L. ; Sampath, S. ; Derbyshire, J.A. ; Bluemke, D.A. ; Gerber, B.L. ; Prince, J.L. ; Osman, N.F.</creatorcontrib><description>Because ECG alterations due to ischemia cannot be reliably detected in the high-field MRI environment, detection of wall motion abnormalities are often the only method to ensure patient safety. In this study, we investigate the use of real-time Harmonic Phase (HARP) MRI for the quantitative, operator-independent detection of the onset of ischemia during acute coronary occlusion. Six mongrel dogs underwent acute coronary artery ischemia of 2 minutes' duration while continuous HARP MR images were acquired followed by 5 minutes of reperfusion. During a second ischemic episode, conventional cine wall motion images were acquired. The time from occlusion to the detection of ischemia by each MR technique, as well as ECG ischemic alterations, was determined. In 5 of 6 animals, the onset of ischemia was detected significantly earlier by HARP than by cine MRI (11 /spl plusmn/ 5 s HARP vs. 34 /spl plusmn/ 14.8 s cine, P<0.03). HARP ischemia detection preceded ECG changes, on average, by 66 seconds. Cine MRI did not detect ischemia significantly earlier than when ECG changes were apparent (P=0.11). The rapid acquisition and detection of ischemia using HARP MRI shows promise as a nonsubjective method to diagnose significant coronary lesions in patients while ensuring patient safety during stress testing.</description><identifier>ISSN: 1094-687X</identifier><identifier>ISBN: 9780780372115</identifier><identifier>ISBN: 0780372115</identifier><identifier>EISSN: 1558-4615</identifier><identifier>DOI: 10.1109/IEMBS.2001.1017313</identifier><language>eng</language><publisher>IEEE</publisher><subject>Arteries ; Dogs ; Electrocardiography ; Ischemic pain ; Magnetic resonance imaging ; Motion detection ; Phase detection ; Safety ; Stress ; Testing</subject><ispartof>2001 Conference Proceedings of the 23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2001, Vol.3, p.2598-2601 vol.3</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://ieeexplore.ieee.org/document/1017313$$EHTML$$P50$$Gieee$$H</linktohtml><link.rule.ids>310,311,781,785,790,791,2059,4051,4052,27929,54924</link.rule.ids><linktorsrc>$$Uhttps://ieeexplore.ieee.org/document/1017313$$EView_record_in_IEEE$$FView_record_in_$$GIEEE</linktorsrc></links><search><creatorcontrib>Kraitchman, D.L.</creatorcontrib><creatorcontrib>Sampath, S.</creatorcontrib><creatorcontrib>Derbyshire, J.A.</creatorcontrib><creatorcontrib>Bluemke, D.A.</creatorcontrib><creatorcontrib>Gerber, B.L.</creatorcontrib><creatorcontrib>Prince, J.L.</creatorcontrib><creatorcontrib>Osman, N.F.</creatorcontrib><title>Quantitative ischemia detection during cardiac MR stress testing</title><title>2001 Conference Proceedings of the 23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society</title><addtitle>IEMBS</addtitle><description>Because ECG alterations due to ischemia cannot be reliably detected in the high-field MRI environment, detection of wall motion abnormalities are often the only method to ensure patient safety. In this study, we investigate the use of real-time Harmonic Phase (HARP) MRI for the quantitative, operator-independent detection of the onset of ischemia during acute coronary occlusion. Six mongrel dogs underwent acute coronary artery ischemia of 2 minutes' duration while continuous HARP MR images were acquired followed by 5 minutes of reperfusion. During a second ischemic episode, conventional cine wall motion images were acquired. The time from occlusion to the detection of ischemia by each MR technique, as well as ECG ischemic alterations, was determined. In 5 of 6 animals, the onset of ischemia was detected significantly earlier by HARP than by cine MRI (11 /spl plusmn/ 5 s HARP vs. 34 /spl plusmn/ 14.8 s cine, P<0.03). HARP ischemia detection preceded ECG changes, on average, by 66 seconds. Cine MRI did not detect ischemia significantly earlier than when ECG changes were apparent (P=0.11). The rapid acquisition and detection of ischemia using HARP MRI shows promise as a nonsubjective method to diagnose significant coronary lesions in patients while ensuring patient safety during stress testing.</description><subject>Arteries</subject><subject>Dogs</subject><subject>Electrocardiography</subject><subject>Ischemic pain</subject><subject>Magnetic resonance imaging</subject><subject>Motion detection</subject><subject>Phase detection</subject><subject>Safety</subject><subject>Stress</subject><subject>Testing</subject><issn>1094-687X</issn><issn>1558-4615</issn><isbn>9780780372115</isbn><isbn>0780372115</isbn><fulltext>true</fulltext><rsrctype>conference_proceeding</rsrctype><creationdate>2001</creationdate><recordtype>conference_proceeding</recordtype><sourceid>6IE</sourceid><sourceid>RIE</sourceid><recordid>eNp9zjsLwjAUBeDgAyzaP6BL_kBrbtNXNlEUHRx8DG4S2qtesVWSVPDf28HZw4EzfMthbAwiBBBqullu54cwEgJCEJBJkB3mQZLkQZxC0mW-ynLRVmYRQNJrTag4SPPsNGC-tXfRRqpYqshjs12ja0dOO3ojJ1vcsCLNS3RYOHrWvGwM1VdeaFOSLvh2z60zaC13aF0rI9a_6IdF_7dDNlktj4t1QIh4fhmqtPmcfz_lf_0C6bs92A</recordid><startdate>2001</startdate><enddate>2001</enddate><creator>Kraitchman, D.L.</creator><creator>Sampath, S.</creator><creator>Derbyshire, J.A.</creator><creator>Bluemke, D.A.</creator><creator>Gerber, B.L.</creator><creator>Prince, J.L.</creator><creator>Osman, N.F.</creator><general>IEEE</general><scope>6IE</scope><scope>6IH</scope><scope>CBEJK</scope><scope>RIE</scope><scope>RIO</scope></search><sort><creationdate>2001</creationdate><title>Quantitative ischemia detection during cardiac MR stress testing</title><author>Kraitchman, D.L. ; Sampath, S. ; Derbyshire, J.A. ; Bluemke, D.A. ; Gerber, B.L. ; Prince, J.L. ; Osman, N.F.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-ieee_primary_10173133</frbrgroupid><rsrctype>conference_proceedings</rsrctype><prefilter>conference_proceedings</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Arteries</topic><topic>Dogs</topic><topic>Electrocardiography</topic><topic>Ischemic pain</topic><topic>Magnetic resonance imaging</topic><topic>Motion detection</topic><topic>Phase detection</topic><topic>Safety</topic><topic>Stress</topic><topic>Testing</topic><toplevel>online_resources</toplevel><creatorcontrib>Kraitchman, D.L.</creatorcontrib><creatorcontrib>Sampath, S.</creatorcontrib><creatorcontrib>Derbyshire, J.A.</creatorcontrib><creatorcontrib>Bluemke, D.A.</creatorcontrib><creatorcontrib>Gerber, B.L.</creatorcontrib><creatorcontrib>Prince, J.L.</creatorcontrib><creatorcontrib>Osman, N.F.</creatorcontrib><collection>IEEE Electronic Library (IEL) Conference Proceedings</collection><collection>IEEE Proceedings Order Plan (POP) 1998-present by volume</collection><collection>IEEE Xplore All Conference Proceedings</collection><collection>IEEE Electronic Library (IEL)</collection><collection>IEEE Proceedings Order Plans (POP) 1998-present</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Kraitchman, D.L.</au><au>Sampath, S.</au><au>Derbyshire, J.A.</au><au>Bluemke, D.A.</au><au>Gerber, B.L.</au><au>Prince, J.L.</au><au>Osman, N.F.</au><format>book</format><genre>proceeding</genre><ristype>CONF</ristype><atitle>Quantitative ischemia detection during cardiac MR stress testing</atitle><btitle>2001 Conference Proceedings of the 23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society</btitle><stitle>IEMBS</stitle><date>2001</date><risdate>2001</risdate><volume>3</volume><spage>2598</spage><epage>2601 vol.3</epage><pages>2598-2601 vol.3</pages><issn>1094-687X</issn><eissn>1558-4615</eissn><isbn>9780780372115</isbn><isbn>0780372115</isbn><abstract>Because ECG alterations due to ischemia cannot be reliably detected in the high-field MRI environment, detection of wall motion abnormalities are often the only method to ensure patient safety. In this study, we investigate the use of real-time Harmonic Phase (HARP) MRI for the quantitative, operator-independent detection of the onset of ischemia during acute coronary occlusion. Six mongrel dogs underwent acute coronary artery ischemia of 2 minutes' duration while continuous HARP MR images were acquired followed by 5 minutes of reperfusion. During a second ischemic episode, conventional cine wall motion images were acquired. The time from occlusion to the detection of ischemia by each MR technique, as well as ECG ischemic alterations, was determined. In 5 of 6 animals, the onset of ischemia was detected significantly earlier by HARP than by cine MRI (11 /spl plusmn/ 5 s HARP vs. 34 /spl plusmn/ 14.8 s cine, P<0.03). HARP ischemia detection preceded ECG changes, on average, by 66 seconds. Cine MRI did not detect ischemia significantly earlier than when ECG changes were apparent (P=0.11). The rapid acquisition and detection of ischemia using HARP MRI shows promise as a nonsubjective method to diagnose significant coronary lesions in patients while ensuring patient safety during stress testing.</abstract><pub>IEEE</pub><doi>10.1109/IEMBS.2001.1017313</doi></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | ISSN: 1094-687X |
| ispartof | 2001 Conference Proceedings of the 23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2001, Vol.3, p.2598-2601 vol.3 |
| issn | 1094-687X 1558-4615 |
| language | eng |
| recordid | cdi_ieee_primary_1017313 |
| source | IEEE Electronic Library (IEL) Conference Proceedings |
| subjects | Arteries Dogs Electrocardiography Ischemic pain Magnetic resonance imaging Motion detection Phase detection Safety Stress Testing |
| title | Quantitative ischemia detection during cardiac MR stress testing |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-17T07%3A02%3A40IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-ieee_6IE&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=proceeding&rft.atitle=Quantitative%20ischemia%20detection%20during%20cardiac%20MR%20stress%20testing&rft.btitle=2001%20Conference%20Proceedings%20of%20the%2023rd%20Annual%20International%20Conference%20of%20the%20IEEE%20Engineering%20in%20Medicine%20and%20Biology%20Society&rft.au=Kraitchman,%20D.L.&rft.date=2001&rft.volume=3&rft.spage=2598&rft.epage=2601%20vol.3&rft.pages=2598-2601%20vol.3&rft.issn=1094-687X&rft.eissn=1558-4615&rft.isbn=9780780372115&rft.isbn_list=0780372115&rft_id=info:doi/10.1109/IEMBS.2001.1017313&rft_dat=%3Cieee_6IE%3E1017313%3C/ieee_6IE%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rft_ieee_id=1017313&rfr_iscdi=true |