Response to Letter to the Editor Regarding "Neutrophil-to-Lymphocyte Ratio in Renal Transplant Patients"
We would like to thank Dr. Yao Yu and Dr. Yisen Zhang for their useful comments about our article. First, we did not conclude that the neutrophil-tolymphocyte ratio (NLR) is a suggestive clinical marker for diagnosing certain solid malignancies. The NLR has been reported as a useful systematic infla...
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| Veröffentlicht in: | Experimental and clinical transplantation 2019-02, Vol.17 (1), p.129-129 |
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| container_title | Experimental and clinical transplantation |
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| creator | Kawahara, Takashi Ohtaka, Mari |
| description | We would like to thank Dr. Yao Yu and Dr. Yisen
Zhang for their useful comments about our article.
First, we did not conclude that the neutrophil-tolymphocyte
ratio (NLR) is a suggestive clinical
marker for diagnosing certain solid malignancies.
The NLR has been reported as a useful systematic
inflammatory response marker in malignancies.1,2 In
addition, previous investigations have shown that
NLR is a useful marker for predicting the prognosis
of various malignant diseases, and a higher NLR has
been associated with a poorer prognosis.3 Our study
concluded that NLR is also influenced by cancer
progression in renal transplant patients.4 Second, as
Dr. Yao and colleagues mentioned, renal transplant
patients in our study received a number of different
drugs for controlling organ resection. We therefore
showed for the first time the changes over time in
NLR in nonmalignant patients receiving steroids and
other immunosuppressive drugs postoperatively. We
then compared the NLR between the nonmalignant
and malignant groups. |
| doi_str_mv | 10.6002/ect.2018.0217R |
| format | Article |
| fullrecord | <record><control><sourceid>pubmed_ideal</sourceid><recordid>TN_cdi_idealonline_journals_IDEAL_90857</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>30719957</sourcerecordid><originalsourceid>FETCH-LOGICAL-c282t-63f834b23eff021436417587920b2a6ed373fde893f36068058d05a7333e754a3</originalsourceid><addsrcrecordid>eNo9kD1PwzAQhi0EolXpyoisLkwpju3EzliV8iFFgKoyW25yaYxSO7Ldof-elALTnXTPe7p7ELpNyTwnhD5AFeeUpHJOaCrWF2hMU54nklNxicYpIzwhMstGaBqC2RLOhaA8l9doxIhIiyITY9SuIfTOBsDR4RJiBH_qYgt4VZvoPF7DTvva2B2evcEhete3pkuiS8rjvm9ddYyA1zoah40dYKs7vPHahr7TNuKPYQI2htkNump0F2D6Wyfo82m1Wb4k5fvz63JRJhWVNCY5ayTjW8qgaYavOMt5KjIpCkq2VOdQM8GaGmTBGpaTXJJM1iTTgjEGIuOaTdD9ea-pQXfOdsaC-nIHPxwW1OvjalGqYtAiBnJ-JivvQvDQqN6bvfZHlRJ18qsGv-rkV_34HQJ350B_2O6h_sf_bLJv1_Z1kw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Response to Letter to the Editor Regarding "Neutrophil-to-Lymphocyte Ratio in Renal Transplant Patients"</title><source>MEDLINE</source><source>EZB-FREE-00999 freely available EZB journals</source><creator>Kawahara, Takashi ; Ohtaka, Mari</creator><contributor>Haberal,Mehmet</contributor><creatorcontrib>Kawahara, Takashi ; Ohtaka, Mari ; the Department of Urology and Renal Transplantation, Yokohama City University Medical Center, Kanagawa, Japan ; Haberal,Mehmet</creatorcontrib><description>We would like to thank Dr. Yao Yu and Dr. Yisen
Zhang for their useful comments about our article.
First, we did not conclude that the neutrophil-tolymphocyte
ratio (NLR) is a suggestive clinical
marker for diagnosing certain solid malignancies.
The NLR has been reported as a useful systematic
inflammatory response marker in malignancies.1,2 In
addition, previous investigations have shown that
NLR is a useful marker for predicting the prognosis
of various malignant diseases, and a higher NLR has
been associated with a poorer prognosis.3 Our study
concluded that NLR is also influenced by cancer
progression in renal transplant patients.4 Second, as
Dr. Yao and colleagues mentioned, renal transplant
patients in our study received a number of different
drugs for controlling organ resection. We therefore
showed for the first time the changes over time in
NLR in nonmalignant patients receiving steroids and
other immunosuppressive drugs postoperatively. We
then compared the NLR between the nonmalignant
and malignant groups.</description><identifier>ISSN: 1304-0855</identifier><identifier>EISSN: 2146-8427</identifier><identifier>DOI: 10.6002/ect.2018.0217R</identifier><identifier>PMID: 30719957</identifier><language>eng</language><publisher>Turkey: Başkent Üniversitesi</publisher><subject>Humans ; Kidney Transplantation ; Lymphocytes ; Neutrophils ; Tıp</subject><ispartof>Experimental and clinical transplantation, 2019-02, Vol.17 (1), p.129-129</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c282t-63f834b23eff021436417587920b2a6ed373fde893f36068058d05a7333e754a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30719957$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Haberal,Mehmet</contributor><creatorcontrib>Kawahara, Takashi</creatorcontrib><creatorcontrib>Ohtaka, Mari</creatorcontrib><creatorcontrib>the Department of Urology and Renal Transplantation, Yokohama City University Medical Center, Kanagawa, Japan</creatorcontrib><title>Response to Letter to the Editor Regarding "Neutrophil-to-Lymphocyte Ratio in Renal Transplant Patients"</title><title>Experimental and clinical transplantation</title><addtitle>Exp Clin Transplant</addtitle><description>We would like to thank Dr. Yao Yu and Dr. Yisen
Zhang for their useful comments about our article.
First, we did not conclude that the neutrophil-tolymphocyte
ratio (NLR) is a suggestive clinical
marker for diagnosing certain solid malignancies.
The NLR has been reported as a useful systematic
inflammatory response marker in malignancies.1,2 In
addition, previous investigations have shown that
NLR is a useful marker for predicting the prognosis
of various malignant diseases, and a higher NLR has
been associated with a poorer prognosis.3 Our study
concluded that NLR is also influenced by cancer
progression in renal transplant patients.4 Second, as
Dr. Yao and colleagues mentioned, renal transplant
patients in our study received a number of different
drugs for controlling organ resection. We therefore
showed for the first time the changes over time in
NLR in nonmalignant patients receiving steroids and
other immunosuppressive drugs postoperatively. We
then compared the NLR between the nonmalignant
and malignant groups.</description><subject>Humans</subject><subject>Kidney Transplantation</subject><subject>Lymphocytes</subject><subject>Neutrophils</subject><subject>Tıp</subject><issn>1304-0855</issn><issn>2146-8427</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kD1PwzAQhi0EolXpyoisLkwpju3EzliV8iFFgKoyW25yaYxSO7Ldof-elALTnXTPe7p7ELpNyTwnhD5AFeeUpHJOaCrWF2hMU54nklNxicYpIzwhMstGaBqC2RLOhaA8l9doxIhIiyITY9SuIfTOBsDR4RJiBH_qYgt4VZvoPF7DTvva2B2evcEhete3pkuiS8rjvm9ddYyA1zoah40dYKs7vPHahr7TNuKPYQI2htkNump0F2D6Wyfo82m1Wb4k5fvz63JRJhWVNCY5ayTjW8qgaYavOMt5KjIpCkq2VOdQM8GaGmTBGpaTXJJM1iTTgjEGIuOaTdD9ea-pQXfOdsaC-nIHPxwW1OvjalGqYtAiBnJ-JivvQvDQqN6bvfZHlRJ18qsGv-rkV_34HQJ350B_2O6h_sf_bLJv1_Z1kw</recordid><startdate>201902</startdate><enddate>201902</enddate><creator>Kawahara, Takashi</creator><creator>Ohtaka, Mari</creator><general>Başkent Üniversitesi</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>IEBAR</scope></search><sort><creationdate>201902</creationdate><title>Response to Letter to the Editor Regarding "Neutrophil-to-Lymphocyte Ratio in Renal Transplant Patients"</title><author>Kawahara, Takashi ; Ohtaka, Mari</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c282t-63f834b23eff021436417587920b2a6ed373fde893f36068058d05a7333e754a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Humans</topic><topic>Kidney Transplantation</topic><topic>Lymphocytes</topic><topic>Neutrophils</topic><topic>Tıp</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kawahara, Takashi</creatorcontrib><creatorcontrib>Ohtaka, Mari</creatorcontrib><creatorcontrib>the Department of Urology and Renal Transplantation, Yokohama City University Medical Center, Kanagawa, Japan</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Idealonline online kütüphane - Journals</collection><jtitle>Experimental and clinical transplantation</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kawahara, Takashi</au><au>Ohtaka, Mari</au><au>Haberal,Mehmet</au><aucorp>the Department of Urology and Renal Transplantation, Yokohama City University Medical Center, Kanagawa, Japan</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Response to Letter to the Editor Regarding "Neutrophil-to-Lymphocyte Ratio in Renal Transplant Patients"</atitle><jtitle>Experimental and clinical transplantation</jtitle><addtitle>Exp Clin Transplant</addtitle><date>2019-02</date><risdate>2019</risdate><volume>17</volume><issue>1</issue><spage>129</spage><epage>129</epage><pages>129-129</pages><issn>1304-0855</issn><eissn>2146-8427</eissn><abstract>We would like to thank Dr. Yao Yu and Dr. Yisen
Zhang for their useful comments about our article.
First, we did not conclude that the neutrophil-tolymphocyte
ratio (NLR) is a suggestive clinical
marker for diagnosing certain solid malignancies.
The NLR has been reported as a useful systematic
inflammatory response marker in malignancies.1,2 In
addition, previous investigations have shown that
NLR is a useful marker for predicting the prognosis
of various malignant diseases, and a higher NLR has
been associated with a poorer prognosis.3 Our study
concluded that NLR is also influenced by cancer
progression in renal transplant patients.4 Second, as
Dr. Yao and colleagues mentioned, renal transplant
patients in our study received a number of different
drugs for controlling organ resection. We therefore
showed for the first time the changes over time in
NLR in nonmalignant patients receiving steroids and
other immunosuppressive drugs postoperatively. We
then compared the NLR between the nonmalignant
and malignant groups.</abstract><cop>Turkey</cop><pub>Başkent Üniversitesi</pub><pmid>30719957</pmid><doi>10.6002/ect.2018.0217R</doi><tpages>1</tpages></addata></record> |
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| ispartof | Experimental and clinical transplantation, 2019-02, Vol.17 (1), p.129-129 |
| issn | 1304-0855 2146-8427 |
| language | eng |
| recordid | cdi_idealonline_journals_IDEAL_90857 |
| source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | Humans Kidney Transplantation Lymphocytes Neutrophils Tıp |
| title | Response to Letter to the Editor Regarding "Neutrophil-to-Lymphocyte Ratio in Renal Transplant Patients" |
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