Intra-Coronary Administration of Tacrolimus Improves Myocardial Perfusion and Left Ventricular Function in Patients with ST-Segment Elevation Myocardial Infarction (COAT-STEMI) Undergoing Primary Percutaneous Coronary Intervention

Background: Ischemia-reperfusion injury following acute ST-segment elevation myocardial infarction (STEMI) is strongly related to inflammation. However, whether intracoronary (IC) tacrolimus, an immunosuppressant, can improve myocardial perfusion is uncertain. <br> Methods: A multicenter double-blin...

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Veröffentlicht in:Acta Cardiologica Sinica 2021-05, Vol.37 (3), p.239-253
Hauptverfasser: Pei-Hsun Sung, Wei-Chun Huang, Ting-Hsing Chao, Cheng-Han Lee, Teng-Yao Yang, Yu-Sheng Lin, Rei-Yeuh Chang, Jun-Ted Chong, Cheng-Hsu Yang, Chieh-Jen Chen, Sheng-Ying Chung, Shu-Kai Hsueh, Chiung-Jen Wu, Hon-Kan Yip
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