Overlay-independent comparisons of X-ray structures reveal small, systematic conformational changes in liganded acetylcholinesterase

Background and Purpose: Comparisons of macromolecular 3D structures by minimizing corresponding atom RMSDs can by virtue of averaging, hide small unexpected deviations caused by ligand binding or site-directed mutagenesis. We developed an overlay-independent comparison approach and used it to compar...

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Veröffentlicht in:	Periodicum biologorum 2017-03, Vol.118 (4), p.319
Hauptverfasser:	Rohrer, Jacqueline, Sidhom, Morgana, Han, Jingting, Radić, Zoran
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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