Comprehensive Analysis of Differential Immunocyte Infiltration and Potential ceRNA Networks Involved in the Development of Atrial Fibrillation

This study is aimed at identifying potential molecular mechanisms and candidate biomarkers in the left atrial regions for the diagnosis and treatment of valvular atrial fibrillation (VAF). Multibioinformatics methods, including linear models for microarray analysis (LIMMA), an SVA algorithm, CIBERSO...

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Veröffentlicht in:	BioMed research international 2020, Vol.2020 (2020), p.1-10, Article 8021208
Hauptverfasser:	Gao, Hong, Ou, Langhui, Wang, Fengxin, Jiang, Siwei, Li, Xiaolong, Wu, Qiang, Chen, Qianghua, Deng, Huiming, Wu, Jiafeng, Ye, Fuyin
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Analysis Annotations Atria Atrial fibrillation Atrial Fibrillation - genetics Atrial Fibrillation - immunology Atrium Biomarkers Biotechnology & Applied Microbiology Cardiac arrhythmia Care and treatment CCR2 protein CD8 antigen CD8-Positive T-Lymphocytes - immunology Data analysis Data processing Deoxyribonucleic acid Diagnosis DNA DNA methylation DNA Methylation - genetics DNA microarrays Fibrillation Gene expression Gene Ontology Gene Regulatory Networks Genes Genomes Genomics Humans Immunocytochemistry Infiltration Life Sciences & Biomedicine Lymphocytes Lymphocytes T Medicine, Research & Experimental Methods MicroRNAs Molecular mechanics Molecular modelling Monocyte chemoattractant protein 1 Neutrophils Principal components analysis Protein interaction Protein-protein interactions Proteins Quality control Research & Experimental Medicine Ribonucleic acid Risk factors RNA RNA - genetics RNA - metabolism RNA, Long Noncoding - genetics RNA, Long Noncoding - metabolism Science & Technology Signal Transduction - genetics
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