Uterine Prostaglandin F2α Content and 20α-Hydroxysteroid Dehydrogenase Activity of Individual Ovarian Compartments During Pseudopregnancy in the Rat
To investigate relationships between prostaglandin F 2α (PGF 2α ) and ovarian 20α-hydroxysteroid dehydrogenase (20α-OH SDH), uterine PGF 2α content and ovarian 20α-OH SDH activity were measured during pseudopregnancy in the rat. Quantitative cytochemical techniques were employed to assess 20α...
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| Veröffentlicht in: | Biology of reproduction 1981-05, Vol.24 (4), p.871 |
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| container_issue | 4 |
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| container_title | Biology of reproduction |
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| creator | JEFFREY A. DOEBLER EDWARD W. WICKERSHAM ADAM ANTHONY |
| description | To investigate relationships between prostaglandin F 2α (PGF 2α ) and ovarian 20α-hydroxysteroid dehydrogenase (20α-OH SDH), uterine PGF 2α content and ovarian 20α-OH SDH activity
were measured during pseudopregnancy in the rat. Quantitative cytochemical techniques were
employed to assess 20α-OH SDH activity in individual compartments of the rat ovary.
The data indicate appreciable 20α-OH SDH activity in corpora of pseudopregnancy, in involuting corpora formed in estrous cycles
prior to pseudopregnancy, and in the interstitial tissue of the
ovary of the pseudopregnant rat. Although enzymatic activity remained unchanged in the latter
two compartments between Days 6 and 15 of pseudopregnancy, a twofold elevation in corpora of
pseudopregnancy 20α-OH SDH activity was evidenced between Days 11 and 15. The close temporal relationship between increased
uterine PGF 2α content (beginning on Days 9-10, peak on Days
11-12) and increased 20α-OH SDH activity in corpora of pseudopregnancy provides further
evidence implicating PGF 2α as the putative factor responsible for inducing luteal 20α-OH SDH
activity during luteal regression in the rat. |
| doi_str_mv | 10.1095/biolreprod24.4.871 |
| format | Article |
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were measured during pseudopregnancy in the rat. Quantitative cytochemical techniques were
employed to assess 20α-OH SDH activity in individual compartments of the rat ovary.
The data indicate appreciable 20α-OH SDH activity in corpora of pseudopregnancy, in involuting corpora formed in estrous cycles
prior to pseudopregnancy, and in the interstitial tissue of the
ovary of the pseudopregnant rat. Although enzymatic activity remained unchanged in the latter
two compartments between Days 6 and 15 of pseudopregnancy, a twofold elevation in corpora of
pseudopregnancy 20α-OH SDH activity was evidenced between Days 11 and 15. The close temporal relationship between increased
uterine PGF 2α content (beginning on Days 9-10, peak on Days
11-12) and increased 20α-OH SDH activity in corpora of pseudopregnancy provides further
evidence implicating PGF 2α as the putative factor responsible for inducing luteal 20α-OH SDH
activity during luteal regression in the rat.</description><identifier>ISSN: 0006-3363</identifier><identifier>EISSN: 1529-7268</identifier><identifier>DOI: 10.1095/biolreprod24.4.871</identifier><identifier>PMID: 6941817</identifier><language>eng</language><publisher>Society for the Study of Reproduction</publisher><ispartof>Biology of reproduction, 1981-05, Vol.24 (4), p.871</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids></links><search><creatorcontrib>JEFFREY A. DOEBLER</creatorcontrib><creatorcontrib>EDWARD W. WICKERSHAM</creatorcontrib><creatorcontrib>ADAM ANTHONY</creatorcontrib><title>Uterine Prostaglandin F2α Content and 20α-Hydroxysteroid Dehydrogenase Activity of Individual Ovarian Compartments During Pseudopregnancy in the Rat</title><title>Biology of reproduction</title><description>To investigate relationships between prostaglandin F 2α (PGF 2α ) and ovarian 20α-hydroxysteroid dehydrogenase (20α-OH SDH), uterine PGF 2α content and ovarian 20α-OH SDH activity
were measured during pseudopregnancy in the rat. Quantitative cytochemical techniques were
employed to assess 20α-OH SDH activity in individual compartments of the rat ovary.
The data indicate appreciable 20α-OH SDH activity in corpora of pseudopregnancy, in involuting corpora formed in estrous cycles
prior to pseudopregnancy, and in the interstitial tissue of the
ovary of the pseudopregnant rat. Although enzymatic activity remained unchanged in the latter
two compartments between Days 6 and 15 of pseudopregnancy, a twofold elevation in corpora of
pseudopregnancy 20α-OH SDH activity was evidenced between Days 11 and 15. The close temporal relationship between increased
uterine PGF 2α content (beginning on Days 9-10, peak on Days
11-12) and increased 20α-OH SDH activity in corpora of pseudopregnancy provides further
evidence implicating PGF 2α as the putative factor responsible for inducing luteal 20α-OH SDH
activity during luteal regression in the rat.</description><issn>0006-3363</issn><issn>1529-7268</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1981</creationdate><recordtype>article</recordtype><sourceid/><recordid>eNqNkEtOwzAURS0EKuWzAUZvwjDBnzSfIWqpyogKwThyGzcxcuzIdhKyCRbALtgCbAxXYgGMrnT03rnSReiG4JjgYnG3k0ZZ0VlT0SRO4jwjJ2hOFrSIMprmp2iOMU4jxlJ2ji6ce8OYJIyyGZqlRUJyks3R56sXVmoBW2uc57XiupIa1vTn4_sLlkZ7oT0ECBQfUbSZKmveJxfejKxgJZojqIXmTsD93stB-gnMAR6DaJBVzxU8DdxKroOu7bj1bVA6WPWht4atE31lOitqzfV-glDuGwHP3F-hswNXTlz_5SW6XT-8LDdRI-tmlFaUruVKdf2OleM40qRMyjAB--_dL6jMahM</recordid><startdate>19810501</startdate><enddate>19810501</enddate><creator>JEFFREY A. DOEBLER</creator><creator>EDWARD W. WICKERSHAM</creator><creator>ADAM ANTHONY</creator><general>Society for the Study of Reproduction</general><scope/></search><sort><creationdate>19810501</creationdate><title>Uterine Prostaglandin F2α Content and 20α-Hydroxysteroid Dehydrogenase Activity of Individual Ovarian Compartments During Pseudopregnancy in the Rat</title><author>JEFFREY A. DOEBLER ; EDWARD W. WICKERSHAM ; ADAM ANTHONY</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-highwire_smallpub3_www24_4_8713</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1981</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>JEFFREY A. DOEBLER</creatorcontrib><creatorcontrib>EDWARD W. WICKERSHAM</creatorcontrib><creatorcontrib>ADAM ANTHONY</creatorcontrib><jtitle>Biology of reproduction</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>JEFFREY A. DOEBLER</au><au>EDWARD W. WICKERSHAM</au><au>ADAM ANTHONY</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Uterine Prostaglandin F2α Content and 20α-Hydroxysteroid Dehydrogenase Activity of Individual Ovarian Compartments During Pseudopregnancy in the Rat</atitle><jtitle>Biology of reproduction</jtitle><date>1981-05-01</date><risdate>1981</risdate><volume>24</volume><issue>4</issue><spage>871</spage><pages>871-</pages><issn>0006-3363</issn><eissn>1529-7268</eissn><abstract>To investigate relationships between prostaglandin F 2α (PGF 2α ) and ovarian 20α-hydroxysteroid dehydrogenase (20α-OH SDH), uterine PGF 2α content and ovarian 20α-OH SDH activity
were measured during pseudopregnancy in the rat. Quantitative cytochemical techniques were
employed to assess 20α-OH SDH activity in individual compartments of the rat ovary.
The data indicate appreciable 20α-OH SDH activity in corpora of pseudopregnancy, in involuting corpora formed in estrous cycles
prior to pseudopregnancy, and in the interstitial tissue of the
ovary of the pseudopregnant rat. Although enzymatic activity remained unchanged in the latter
two compartments between Days 6 and 15 of pseudopregnancy, a twofold elevation in corpora of
pseudopregnancy 20α-OH SDH activity was evidenced between Days 11 and 15. The close temporal relationship between increased
uterine PGF 2α content (beginning on Days 9-10, peak on Days
11-12) and increased 20α-OH SDH activity in corpora of pseudopregnancy provides further
evidence implicating PGF 2α as the putative factor responsible for inducing luteal 20α-OH SDH
activity during luteal regression in the rat.</abstract><pub>Society for the Study of Reproduction</pub><pmid>6941817</pmid><doi>10.1095/biolreprod24.4.871</doi></addata></record> |
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| ispartof | Biology of reproduction, 1981-05, Vol.24 (4), p.871 |
| issn | 0006-3363 1529-7268 |
| language | eng |
| recordid | cdi_highwire_smallpub3_www24_4_871 |
| source | EZB-FREE-00999 freely available EZB journals |
| title | Uterine Prostaglandin F2α Content and 20α-Hydroxysteroid Dehydrogenase Activity of Individual Ovarian Compartments During Pseudopregnancy in the Rat |
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