Expression of Estrogen Receptor-α Protein in the Rat Digestive Tract
The current study evaluates the expression of estrogen receptor-α (ER-α) protein in the digestive tract and other organs using immunohistochemistry in male and female intact rats. As a result, the expression of ER-α protein was intensively immunoreactive in the nuclei of squamous epithelium of th...
Gespeichert in:
| Veröffentlicht in: | In vivo (Athens) 2007-05, Vol.21 (3), p.487 |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | 3 |
| container_start_page | 487 |
| container_title | In vivo (Athens) |
| container_volume | 21 |
| creator | KENTARO GEJIMA HIROAKI KAWAGUCHI MASAKAZU SOUDA HIDEO KAWASHIMA TERUO KOMOKATA NOBUO HAMADA YOSHIHISA UMEKITA RYUZO SAKATA HIROKI YOSHIDA |
| description | The current study evaluates the expression of estrogen receptor-α (ER-α) protein in the digestive tract and other organs using
immunohistochemistry in male and female intact rats. As a result, the expression of ER-α protein was intensively immunoreactive
in the nuclei of squamous epithelium of the forestomach connected to the limiting ridge and the anus connected to the anorectal
junction. Rat ER-α mRNA signals were also detected in the epithelium of the limiting ridge using in situ hybridization. The
incidence of ER-α protein in the limiting ridge decreased with age in both males and females. The incidence of ER-α protein
in the anorectal junction strongly decreased with age in males, although the incidence did not decrease with age in females.
In conclusion, it was suggested that estrogen may be involved in the proliferation and differentiation of these cells in the
limiting ridge of the stomach and anorectal junction of rats. |
| format | Article |
| fullrecord | <record><control><sourceid>highwire</sourceid><recordid>TN_cdi_highwire_smallpub3_iv21_3_487</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>iv21_3_487</sourcerecordid><originalsourceid>FETCH-highwire_smallpub3_iv21_3_4873</originalsourceid><addsrcrecordid>eNqNyj0OgjAYgOHGaBR_7tDBlaQFamFW1NEQBremkg-oQUraip7Cu3gFvZgOHsDkTZ7lHSCP8oT6nEXJEHkkYLEfM3qcoKm1Z0JWnJBgjCaUs4SGLPbQLr13BqxVusW6xKl1RlfQ4gwK6Jw2_vvxeuKD0Q5Ui7-5GnAmHd6oCqxTPeDcyMLN0aiUjYXFzxlabtN8vfdrVdU3ZUDYi2ya7noKheoDKkIRxTz8c_sAmTtBNA</addsrcrecordid><sourcetype>Publisher</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Expression of Estrogen Receptor-α Protein in the Rat Digestive Tract</title><source>EZB-FREE-00999 freely available EZB journals</source><creator>KENTARO GEJIMA ; HIROAKI KAWAGUCHI ; MASAKAZU SOUDA ; HIDEO KAWASHIMA ; TERUO KOMOKATA ; NOBUO HAMADA ; YOSHIHISA UMEKITA ; RYUZO SAKATA ; HIROKI YOSHIDA</creator><creatorcontrib>KENTARO GEJIMA ; HIROAKI KAWAGUCHI ; MASAKAZU SOUDA ; HIDEO KAWASHIMA ; TERUO KOMOKATA ; NOBUO HAMADA ; YOSHIHISA UMEKITA ; RYUZO SAKATA ; HIROKI YOSHIDA</creatorcontrib><description>The current study evaluates the expression of estrogen receptor-α (ER-α) protein in the digestive tract and other organs using
immunohistochemistry in male and female intact rats. As a result, the expression of ER-α protein was intensively immunoreactive
in the nuclei of squamous epithelium of the forestomach connected to the limiting ridge and the anus connected to the anorectal
junction. Rat ER-α mRNA signals were also detected in the epithelium of the limiting ridge using in situ hybridization. The
incidence of ER-α protein in the limiting ridge decreased with age in both males and females. The incidence of ER-α protein
in the anorectal junction strongly decreased with age in males, although the incidence did not decrease with age in females.
In conclusion, it was suggested that estrogen may be involved in the proliferation and differentiation of these cells in the
limiting ridge of the stomach and anorectal junction of rats.</description><identifier>ISSN: 0258-851X</identifier><identifier>EISSN: 1791-7549</identifier><identifier>PMID: 17591358</identifier><language>eng</language><publisher>International Institute of Anticancer Research</publisher><ispartof>In vivo (Athens), 2007-05, Vol.21 (3), p.487</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781</link.rule.ids></links><search><creatorcontrib>KENTARO GEJIMA</creatorcontrib><creatorcontrib>HIROAKI KAWAGUCHI</creatorcontrib><creatorcontrib>MASAKAZU SOUDA</creatorcontrib><creatorcontrib>HIDEO KAWASHIMA</creatorcontrib><creatorcontrib>TERUO KOMOKATA</creatorcontrib><creatorcontrib>NOBUO HAMADA</creatorcontrib><creatorcontrib>YOSHIHISA UMEKITA</creatorcontrib><creatorcontrib>RYUZO SAKATA</creatorcontrib><creatorcontrib>HIROKI YOSHIDA</creatorcontrib><title>Expression of Estrogen Receptor-α Protein in the Rat Digestive Tract</title><title>In vivo (Athens)</title><description>The current study evaluates the expression of estrogen receptor-α (ER-α) protein in the digestive tract and other organs using
immunohistochemistry in male and female intact rats. As a result, the expression of ER-α protein was intensively immunoreactive
in the nuclei of squamous epithelium of the forestomach connected to the limiting ridge and the anus connected to the anorectal
junction. Rat ER-α mRNA signals were also detected in the epithelium of the limiting ridge using in situ hybridization. The
incidence of ER-α protein in the limiting ridge decreased with age in both males and females. The incidence of ER-α protein
in the anorectal junction strongly decreased with age in males, although the incidence did not decrease with age in females.
In conclusion, it was suggested that estrogen may be involved in the proliferation and differentiation of these cells in the
limiting ridge of the stomach and anorectal junction of rats.</description><issn>0258-851X</issn><issn>1791-7549</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid/><recordid>eNqNyj0OgjAYgOHGaBR_7tDBlaQFamFW1NEQBremkg-oQUraip7Cu3gFvZgOHsDkTZ7lHSCP8oT6nEXJEHkkYLEfM3qcoKm1Z0JWnJBgjCaUs4SGLPbQLr13BqxVusW6xKl1RlfQ4gwK6Jw2_vvxeuKD0Q5Ui7-5GnAmHd6oCqxTPeDcyMLN0aiUjYXFzxlabtN8vfdrVdU3ZUDYi2ya7noKheoDKkIRxTz8c_sAmTtBNA</recordid><startdate>20070501</startdate><enddate>20070501</enddate><creator>KENTARO GEJIMA</creator><creator>HIROAKI KAWAGUCHI</creator><creator>MASAKAZU SOUDA</creator><creator>HIDEO KAWASHIMA</creator><creator>TERUO KOMOKATA</creator><creator>NOBUO HAMADA</creator><creator>YOSHIHISA UMEKITA</creator><creator>RYUZO SAKATA</creator><creator>HIROKI YOSHIDA</creator><general>International Institute of Anticancer Research</general><scope/></search><sort><creationdate>20070501</creationdate><title>Expression of Estrogen Receptor-α Protein in the Rat Digestive Tract</title><author>KENTARO GEJIMA ; HIROAKI KAWAGUCHI ; MASAKAZU SOUDA ; HIDEO KAWASHIMA ; TERUO KOMOKATA ; NOBUO HAMADA ; YOSHIHISA UMEKITA ; RYUZO SAKATA ; HIROKI YOSHIDA</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-highwire_smallpub3_iv21_3_4873</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>KENTARO GEJIMA</creatorcontrib><creatorcontrib>HIROAKI KAWAGUCHI</creatorcontrib><creatorcontrib>MASAKAZU SOUDA</creatorcontrib><creatorcontrib>HIDEO KAWASHIMA</creatorcontrib><creatorcontrib>TERUO KOMOKATA</creatorcontrib><creatorcontrib>NOBUO HAMADA</creatorcontrib><creatorcontrib>YOSHIHISA UMEKITA</creatorcontrib><creatorcontrib>RYUZO SAKATA</creatorcontrib><creatorcontrib>HIROKI YOSHIDA</creatorcontrib><jtitle>In vivo (Athens)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>KENTARO GEJIMA</au><au>HIROAKI KAWAGUCHI</au><au>MASAKAZU SOUDA</au><au>HIDEO KAWASHIMA</au><au>TERUO KOMOKATA</au><au>NOBUO HAMADA</au><au>YOSHIHISA UMEKITA</au><au>RYUZO SAKATA</au><au>HIROKI YOSHIDA</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Expression of Estrogen Receptor-α Protein in the Rat Digestive Tract</atitle><jtitle>In vivo (Athens)</jtitle><date>2007-05-01</date><risdate>2007</risdate><volume>21</volume><issue>3</issue><spage>487</spage><pages>487-</pages><issn>0258-851X</issn><eissn>1791-7549</eissn><abstract>The current study evaluates the expression of estrogen receptor-α (ER-α) protein in the digestive tract and other organs using
immunohistochemistry in male and female intact rats. As a result, the expression of ER-α protein was intensively immunoreactive
in the nuclei of squamous epithelium of the forestomach connected to the limiting ridge and the anus connected to the anorectal
junction. Rat ER-α mRNA signals were also detected in the epithelium of the limiting ridge using in situ hybridization. The
incidence of ER-α protein in the limiting ridge decreased with age in both males and females. The incidence of ER-α protein
in the anorectal junction strongly decreased with age in males, although the incidence did not decrease with age in females.
In conclusion, it was suggested that estrogen may be involved in the proliferation and differentiation of these cells in the
limiting ridge of the stomach and anorectal junction of rats.</abstract><pub>International Institute of Anticancer Research</pub><pmid>17591358</pmid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0258-851X |
| ispartof | In vivo (Athens), 2007-05, Vol.21 (3), p.487 |
| issn | 0258-851X 1791-7549 |
| language | eng |
| recordid | cdi_highwire_smallpub3_iv21_3_487 |
| source | EZB-FREE-00999 freely available EZB journals |
| title | Expression of Estrogen Receptor-α Protein in the Rat Digestive Tract |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-17T22%3A14%3A44IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-highwire&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Expression%20of%20Estrogen%20Receptor-%C3%8E%C2%B1%20Protein%20in%20the%20Rat%20Digestive%20Tract&rft.jtitle=In%20vivo%20(Athens)&rft.au=KENTARO%20GEJIMA&rft.date=2007-05-01&rft.volume=21&rft.issue=3&rft.spage=487&rft.pages=487-&rft.issn=0258-851X&rft.eissn=1791-7549&rft_id=info:doi/&rft_dat=%3Chighwire%3Eiv21_3_487%3C/highwire%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/17591358&rfr_iscdi=true |