Indirubin-3′-monoxime, a CDK Inhibitor Induces Growth Inhibition and Apoptosis-independent Up-regulation of Survivin in Transitional Cell Cancer

In traditional Chinese Medicine, the preparation Danggui Longhui Wan has been used for years in the treatment of chronic myelocytic leukemia. The compound indirubin has been shown to be the active constituent. A cell permeable derivative, indirubin-3′-monoxime, is a selective and potent inhibitor...

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Veröffentlicht in:	Anticancer research 2006-05, Vol.26 (3A), p.2129
Hauptverfasser:	FRANK G.E. PERABO, CHRISTIAN FRÖSSLER, GREGOR LANDWEHRS, DORIS H. SCHMIDT, ALEXANDER VON RÜCKER, ANDREAS WIRGER, STEFAN C. MÜLLER
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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