The supportive effects of IL-7 on eosinophil progenitors from human bone marrow cells can be blocked by anti-IL-5

Human rIL-7 was studied for its effects on myeloid and erythroid progenitors from human bone marrow cells. IL-7 did not support the granulocytic/monocytic or erythroid lineage but exclusively stimulated eosinophil colony formation (CFU-Eo) (4 +/- 3 vs 48 +/- 17 CFU-Eo/10(5) nonadherent fraction-non-...

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Veröffentlicht in:The Journal of immunology (1950) 1992-11, Vol.149 (9), p.2992-2995
Hauptverfasser: Vellenga, E, Esselink, MT, Straaten, J, Stulp, BK, De Wolf, JT, Brons, R, Giannotti, J, Smit, JW, Halie, MR
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Sprache:eng
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