Upregulation of renin-angiotensin system and downregulation of kallikrein in obstructive nephropathy

S. S. el-Dahr, J. Gee, S. Dipp, B. G. Hanss, R. C. Vari and J. Chao Department of Pediatrics, Tulane University School of Medicine, New Orleans, Louisiana 70112. The purpose of this study was to delineate the effects of prolonged (1 and 5 wk) unilateral ureteral obstruction (UUO) on the intrarenal r...

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Veröffentlicht in:	American journal of physiology. Renal, fluid and electrolyte physiology fluid and electrolyte physiology, 1993-05, Vol.264 (5), p.874-F881
Hauptverfasser:	el-Dahr, S. S, Gee, J, Dipp, S, Hanss, B. G, Vari, R. C, Chao, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin II - antagonists & inhibitors Angiotensin II - blood Angiotensin II - metabolism Animals Biphenyl Compounds - pharmacology Blood Pressure - drug effects Gene Expression Imidazoles - pharmacology Kallikreins - genetics Kallikreins - metabolism Kidney - metabolism Kidney Diseases - etiology Kidney Diseases - metabolism Losartan Male Rats Rats, Sprague-Dawley Renin-Angiotensin System - genetics RNA, Messenger - metabolism Tetrazoles - pharmacology Ureteral Obstruction - complications Ureteral Obstruction - metabolism
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