Ketone body effects on glutamine metabolism in isolated kidneys and mitochondria

L. Goldstein, R. J. Solomon, D. F. Perlman, P. M. McLaughlin and M. A. Taylor beta-Hydroxybutyrate (but not acetoacetate) caused marked inhibition of ammonia production and glutamine extraction in isolated perfused kidneys from normal rats. Glutamine synthesis was not affected by beta-hydroxybutyrat...

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Veröffentlicht in:	American journal of physiology. Renal physiology 1982-08, Vol.243 (2), p.181-F187
Hauptverfasser:	Goldstein, L, Solomon, R. J, Perlman, D. F, McLaughlin, P. M, Taylor, M. A
Format:	Artikel
Sprache:	eng
Schlagworte:	3-Hydroxybutyric Acid Ammonia - metabolism Animals Glomerular Filtration Rate Glutamate Dehydrogenase - metabolism Glutamine - metabolism Hydroxybutyrates - pharmacology Ketone Bodies - pharmacology Kidney - metabolism Kidney - ultrastructure Male Mitochondria - enzymology Mitochondria - metabolism NAD - metabolism Rats Rats, Inbred Strains Urination
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