Regulation of fetal cardiac and hepatic beta -adrenoceptors and adenylyl cyclase signaling: terbutaline effects

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710 Terbutaline (Ter), a 2 -adrenergic agonist used in preterm labor, stimulates fetal -adrenoceptors ( -ARs). We administered Ter to pregnant rats on gestational days 17-20 and examined -ARs and...

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Veröffentlicht in:	American journal of physiology. Regulatory, integrative and comparative physiology integrative and comparative physiology, 2001-10, Vol.281 (4), p.1079-R1089
Hauptverfasser:	Auman, J. T, Seidler, F. J, Slotkin, T. A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenylyl Cyclases - metabolism Adrenergic alpha-Agonists - pharmacology Adrenergic beta-Agonists - pharmacology Animals Down-Regulation - drug effects Enzyme Induction - drug effects Female Fetal Weight - drug effects Fetus - drug effects Fetus - metabolism GTP-Binding Proteins - metabolism Liver - metabolism Male Maternal-Fetal Exchange - physiology Myocardium - metabolism Organ Size - drug effects Pregnancy Rats Receptors, Adrenergic, beta - metabolism Signal Transduction - drug effects Signal Transduction - physiology Terbutaline - pharmacology
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