Early evening melatonin and S-20098 advance circadian phase and nocturnal regulation of core body temperature

K. Krauchi, C. Cajochen, D. Mori, P. Graw and A. Wirz-Justice Psychiatric University Clinic, Basel, Switzerland. The phase-shifting capacity and thermoregulatory effects of a single oral administration at 18 h of melatonin (5 mg) or S-20098, a melatonin agonist (5 or 100 mg), was investigated in eig...

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