Serotonergic activity is depressed in the ventromedial hypothalamic nucleus of 12-day-old obese Zucker rats

We previously reported lower ventromedial hypothalamic nucleus (VMN) serotonergic activity in 11-wk genetically obese vs. lean Zucker rats. To determine whether the activity was secondary to metabolic alterations associated with this established obesity (e.g., significant hyperphagia and hyperinsuli...

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Veröffentlicht in:	American journal of physiology. Regulatory, integrative and comparative physiology integrative and comparative physiology, 1994-09, Vol.267 (3), p.R712-R719
Hauptverfasser:	Routh, V.H, Stern, J.S, Horwitz, B.A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose Tissue - pathology Animals Animals, Newborn - growth & development Body Weight Dopamine - metabolism Genotype Heterozygote Homozygote Hydroxyindoleacetic Acid - metabolism Hyperinsulinism - etiology hypothalamus insulin Insulin - blood monoamines obesity Obesity - complications Obesity - metabolism Obesity - pathology Rats Rats, Zucker - metabolism Reference Values serotonin Serotonin - metabolism Ventromedial Hypothalamic Nucleus - metabolism young animals
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