Cholecystokinin octapeptide analogues suppress food intake via central CCK-A receptors in mice

To examine the mechanism of satiety-producing effect of cholecystokinin (CCK) in the central nervous system, we compared the potency of intraperitoneally (ip) or intracerebroventricularly (icv) administered CCK-8 and its analogues on food intake in fasted mice. The icv administration of a small dose...

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Veröffentlicht in:	American journal of physiology. Regulatory, integrative and comparative physiology integrative and comparative physiology, 1993-09, Vol.265 (3), p.481-R486
Hauptverfasser:	Hirosue, Y, Inui, A, Teranishi, A, Miura, M, Nakajima, M, Okita, M, Nakajima, Y, Himori, N, Baba, S, Kasuga, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals apetito appetit appetite Benzodiazepinones - pharmacology Brain - metabolism central nervous system chemoreceptors chimiorecepteur Cholecystokinin - analogs & derivatives Cholecystokinin - blood Cholecystokinin - physiology Devazepide Eating - drug effects Fasting food intake gastrointestinal hormones hormonas gastrointestinales hormone gastrointestinale ingestion de alimentos Injections, Intraperitoneal Injections, Intraventricular Male Mice Molecular Sequence Data Phenylurea Compounds prise alimentaire homme quimioreceptors raton Receptors, Cholecystokinin - physiology Sincalide - analogs & derivatives Sincalide - pharmacology sistema nervioso central souris systeme nerveux central
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