Smooth muscle cell-specific transcription is regulated by nuclear localization of the myocardin-related transcription factors

Department of Pathology and Laboratory Medicine and the Carolina Cardiovascular Biology Center, University of North Carolina, Chapel Hill, North Carolina Submitted 10 August 2006 ; accepted in final form 14 September 2006 On the basis of our previous studies on RhoA signaling in smooth muscle cells...

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Veröffentlicht in:	American journal of physiology. Heart and circulatory physiology 2007-02, Vol.292 (2), p.H1170-H1180
Hauptverfasser:	Hinson, Jeremiah S, Medlin, Matthew D, Lockman, Kashelle, Taylor, Joan M, Mack, Christopher P
Format:	Artikel
Sprache:	eng
Schlagworte:	Active Transport, Cell Nucleus - drug effects Animals Aorta, Thoracic - metabolism Cell Differentiation Cell Nucleus - drug effects Cell Nucleus - metabolism Cells Cells, Cultured Cytoskeleton Genotype & phenotype Lysophospholipids - pharmacology Microfilament Proteins - genetics Microfilament Proteins - metabolism Muscle Proteins - genetics Muscle Proteins - metabolism Muscle, Smooth, Vascular - drug effects Muscle, Smooth, Vascular - metabolism Muscular system Mutation Myocytes, Smooth Muscle - cytology Myocytes, Smooth Muscle - drug effects Myocytes, Smooth Muscle - metabolism Nuclear Proteins - genetics Nuclear Proteins - metabolism Phenotype Platelet-Derived Growth Factor - pharmacology Promoter Regions, Genetic - drug effects Rats rhoA GTP-Binding Protein - metabolism RNA, Messenger - metabolism Serum Response Factor - metabolism Sphingosine - analogs & derivatives Sphingosine - pharmacology Time Factors Trans-Activators - genetics Trans-Activators - metabolism Transcription, Genetic - drug effects Transfection Transforming Growth Factor beta - pharmacology
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