G protein modulates thyroid hormone-induced Na+ channel activation in ventricular myocytes

Division of Cardiology, Department of Medicine, The David Geffen School of Medicine, University of California, Los Angeles, California 90095 To evaluate the effects of liothyronine (3,5,3'-triiodo- L -thyronine, T 3 ) on Na + channel current ( I Na ) properties, I Na was recorded in adult guine...

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Veröffentlicht in:	American journal of physiology. Heart and circulatory physiology 2002-11, Vol.283 (5), p.H2119-H2129
Hauptverfasser:	Sen, Luyi, Sakaguchi, Yoshihide, Cui, Guanggen
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals GTP-Binding Proteins - metabolism Guanosine 5'-O-(3-Thiotriphosphate) - pharmacology Guinea Pigs Ion Channel Gating - drug effects Ion Channel Gating - physiology Male Membrane Potentials - drug effects Membrane Potentials - physiology Myocytes, Cardiac - drug effects Myocytes, Cardiac - metabolism Patch-Clamp Techniques Pertussis Toxin - pharmacology Sodium Channels - metabolism Triiodothyronine - pharmacology
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