Activation of spinal opioid receptors contributes to hypotension after hemorrhage in conscious rats

1 Cardiovascular Neuroscience Group, Cardiovascular Medicine and Centre for Neuroscience, Flinders University, Bedford Park, SA 5042; and 2 Royal North Shore Hospital, St. Leonards, NSW 2065, Australia Opioid receptors are activated during severe hemorrhage, resulting in sympathoinhibition and a p...

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Veröffentlicht in:	American journal of physiology. Heart and circulatory physiology 1999-05, Vol.276 (5), p.H1552-H1558
Hauptverfasser:	Ang, Kooi K, McRitchie, Robert J, Minson, Jane B, Llewellyn-Smith, Ida J, Pilowsky, Paul M, Chalmers, John P, Arnolda, Leonard F
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blood Pressure - physiology Consciousness Dynorphins - physiology Endorphins - physiology Enkephalin, Leucine - analogs & derivatives Enkephalin, Leucine - pharmacology Heart Rate - physiology Hemorrhage - complications Hemorrhage - physiopathology Hypotension - etiology Hypotension - physiopathology Male Naloxone - pharmacology Narcotic Antagonists - pharmacology Neural Inhibition - drug effects Rats Rats, Inbred WKY Receptors, Opioid, kappa - physiology Receptors, Opioid, mu - physiology Somatostatin - analogs & derivatives Somatostatin - pharmacology Spinal Cord - chemistry Spinal Cord - drug effects Sympathetic Nervous System - drug effects Sympathetic Nervous System - physiology
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