Functional overload increases beta -MHC promoter activity in rodent fast muscle via the proximal MCAT (beta e3) site

Department of Physiology and Biophysics, University of California, Irvine, California 92697 Functional overload (OL) of the rat plantaris muscle by the removal of synergistic muscles induces a shift in the myosin heavy chain (MHC) isoform expression profile from the fast isoforms toward the slow typ...

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Veröffentlicht in:	American Journal of Physiology: Cell Physiology 2002-03, Vol.282 (3), p.C518-C527
Hauptverfasser:	Giger, Julia M, Haddad, Fadia, Qin, Anqi X, Baldwin, Kenneth M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomechanical Phenomena Body Weight Female Genes, Reporter Humans Hypertrophy Muscle Fibers, Fast-Twitch Muscle, Skeletal - physiology Mutagenesis, Site-Directed Myosin Heavy Chains - genetics Myosin Heavy Chains - metabolism Nuclear Proteins - genetics Nuclear Proteins - metabolism Organ Size Promoter Regions, Genetic Protein Isoforms Rats Rats, Sprague-Dawley Stress, Mechanical
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