Mechanotransduction in bone: osteoblasts are more responsive to fluid forces than mechanical strain

I. Owan, D. B. Burr, C. H. Turner, J. Qiu, Y. Tu, J. E. Onyia and R. L. Duncan Department of Anatomy, Indiana University Medical Center, Indianapolis 46202, USA. Mechanical force applied to bone produces two localized mechanical signals on the cell: deformation of the extracellular matrix (substrate...

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