Biosynthetic and growth abnormalities are associated with high-level expression of CFTR in heterologous cells

S. C. Schiavi, N. Abdelkader, S. Reber, S. Pennington, R. Narayana, J. M. McPherson, A. E. Smith, H. Hoppe 4th and S. H. Cheng Genzyme Corporation, Framingham, Massachusetts 01701-9322, USA. An inducible gene amplification system was utilized to study the effects of overexpression of cystic fibrosis...

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Veröffentlicht in:	American Journal of Physiology: Cell Physiology 1996-01, Vol.270 (1), p.C341-C351
Hauptverfasser:	Schiavi, S. C, Abdelkader, N, Reber, S, Pennington, S, Narayana, R, McPherson, J. M, Smith, A. E, Hoppe, H., 4th, Cheng, S. H
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Division Cell Line Cell Physiological Phenomena Cells - cytology Cells - metabolism Cystic Fibrosis Transmembrane Conductance Regulator - genetics Cystic Fibrosis Transmembrane Conductance Regulator - metabolism G2 Phase Haplorhini Kidney - cytology Kidney - metabolism Mitosis Mutation RNA, Messenger - metabolism Time Factors Transfection
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