Different Internalization Properties of the α1a- and α1b-Adrenergic Receptor Subtypes: The Potential Role of Receptor Interaction with β-Arrestins and AP50

The internalization properties of the α1a- and α1b-adrenergic receptors (ARs) subtypes transiently expressed in human embryonic kidney (HEK) 293 cells were compared using biotinylation experiments and confocal microscopy. Whereas the α1b-AR displayed robust agonist-induced endocytosis, the α1a-A...

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Veröffentlicht in:	Molecular pharmacology 2008-09, Vol.74 (3), p.562
Hauptverfasser:	Laura Stanasila, Liliane Abuin, Julien Dey, Susanna Cotecchia
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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