The Size of a Single Residue of the Sulfonylurea Receptor Dictates the Effectiveness of KATP Channel Openers

KATP channel openers are a diverse group of molecules able to activate ATP-sensitive K+ channels in a tissue-dependent manner by binding to the channel regulatory subunit, the sulfonylurea receptor (SUR), an ATP-binding cassette protein. Residues crucial to this action were previously identified in...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Molecular pharmacology 2005-04, Vol.67 (4), p.1026-1033
Hauptverfasser:	Moreau, Christophe, Gally, Fabienne, Jacquet-Bouix, Heélène, Vivaudou, Michel
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!