Membrane Structure Modulation, Protein Kinase Cα Activation, and Anticancer Activity of Minerval

Most drugs currently used for human therapy interact with proteins, altering their activity to modulate the pathological cell physiology. In contrast, 2-hydroxy-9- cis -octadecenoic acid (Minerval) was designed to modify the lipid organization of the membrane. Its structure was deduced following the...

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Veröffentlicht in:Molecular pharmacology 2005-02, Vol.67 (2), p.531
Hauptverfasser: Jordi Martínez, Oliver Vögler, Jesús Casas, Francisca BarcelÃ, Regina Alemany, Jesús Prades, Tünde Nagy, Carmela Baamonde, Philip G. Kasprzyk, Silvia Terés, Carlos Saus, Pablo V. EscribÃ
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Sprache:eng
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