Specific Inhibition of Nuclear Factor-κB–Dependent Inflammatory Responses by Cell Type-Specific Mechanisms upon A2A Adenosine Receptor Gene Transfer

Adenosine is a potent inhibitor of inflammatory processes, and the A 2A adenosine receptor (A 2A AR) plays a key nonredundant role as a suppresser of inflammatory responses in vivo. In this study, we demonstrate that increasing A 2A AR gene expression suppressed multiple inflammatory responses in bo...

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Veröffentlicht in:Molecular pharmacology 2004-11, Vol.66 (5), p.1147
Hauptverfasser: William A. Sands, Anthony F. Martin, Elaine W. Strong, Timothy M. Palmer
Format: Artikel
Sprache:eng
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