A Fusion Protein of the Human P2Y1 Receptor and NTPDase1 Exhibits Functional Activities of the Native Receptor and Ectoenzyme and Reduced Signaling Responses to Endogenously Released Nucleotides

To begin to address the functional interactions between constitutively released nucleotides, ectonucleotidase activity, and P2Y receptor-promoted signaling responses, we engineered the human P2Y 1 receptor in a fusion protein with a member of the ectonucleoside triphosphate diphosphohydrolase family...

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Veröffentlicht in:Molecular pharmacology 2002-09, Vol.62 (3), p.521
Hauptverfasser: Claudia Alvarado-Castillo, Patricia Lozano-Zarain, Jesús Mateo, T. Kendall Harden, José L. Boyer
Format: Artikel
Sprache:eng ; jpn
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