pS2 Gene Expression in HepG2 cells: Complex Regulation through Crosstalk between the Estrogen Receptor α, an Estrogen-Responsive Element, and the Activator Protein 1 Response Element

The pS2 promoter is complex with binding sites for a number of protein factors that may participate in modulating its activity. The pS2 gene was transcriptionally activated by estrogens in HepG2 cells transformed (HepER3) to express the estrogen receptor α (ERα). The phorbol ester phorbol 12-myris...

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Veröffentlicht in:Molecular pharmacology 2002-06, Vol.61 (6), p.1273
Hauptverfasser: Tomas Barkhem, Lars-Arne Haldosén, Jan-Åke Gustafsson, Stefan Nilsson
Format: Artikel
Sprache:eng
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