Induction of Differentiation in F9 Cells and Activation of Peroxisome Proliferator-Activated Receptor δ by Valproic Acid and Its Teratogenic Derivatives

The antiepileptic drug valproic acid (VPA) is teratogenic, because it induces birth defects in some children of mothers treated for epilepsy. Cellular and molecular actions associated with teratogenicity were identified by testing differentiation of F9 embryocarcinoma cells. VPA altered cell morphol...

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Veröffentlicht in:	Molecular pharmacology 2001-05, Vol.59 (5), p.1269
Hauptverfasser:	Uwe Werling, Sandra Siehler, Margarethe Litfin, Heinz Nau, Martin Göttlicher
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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