Kinetic Analysis of Agonist-Induced Down-Regulation of the β2-Adrenergic Receptor in BEAS-2B Cells Reveals High- and Low-Affinity Components

We examined the interrelationships of internalization and down-regulation of the β 2 -adrenergic receptor in response to treatment of the BEAS-2B human epithelial cell line with both a series of agonists at high occupancy and with various concentrations of fenoterol that gave occupancies from 0.93...

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Veröffentlicht in:	Molecular pharmacology 2000-08, Vol.58 (2), p.421
Hauptverfasser:	Bruce R. Williams, Roger Barber, Richard B. Clark
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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