The Effects of Repeated Opioid Administration on Locomotor Activity: I. Opposing Actions of μ and κ Receptors

Repeated administration of many addictive drugs leads to a progressive increase in their locomotor effects. This increase in locomotor activity often develops concomitantly with increases in their positive-reinforcing effects, which are believed to contribute to the etiology of substance use disorde...

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Veröffentlicht in:The Journal of pharmacology and experimental therapeutics 2009-08, Vol.330 (2), p.468
Hauptverfasser: Mark A. Smith, Jennifer L. Greene-Naples, Megan A. Lyle, Jordan C. Iordanou, Jennifer N. Felder
Format: Artikel
Sprache:eng
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