Periodontal Changes in Children and Adolescents With Diabetes

Periodontal Changes in Children and Adolescents With Diabetes A case-control study Evanthia Lalla , DDS 1 , Bin Cheng , PHD 2 , Shantanu Lal , DDS 1 , Sid Tucker , DDS 1 , Ellen Greenberg , MS 3 , Robin Goland , MD 3 and Ira B. Lamster , DDS 1 1 School of Dental and Oral Surgery, Columbia University Medical Center, New York, New York 2 Mailman School of Public Health, Columbia University Medical Center, New York, New York 3 Naomi Berrie Diabetes Center, Columbia University Medical Center, New York, New York Address correspondence and reprint requests to Evanthia Lalla, DDS, MS, Associate Professor of Dentistry, Division of Periodontics, Columbia University School of DentalOral Surgery, 630 W. 168th St., PH7E-110, New York, NY 10032. E-mail: el94{at}columbia.edu Abstract OBJECTIVE —To evaluate the level of oral disease in children and adolescents with diabetes. RESEARCH DESIGN AND METHODS —Dental caries and periodontal disease were clinically assessed in 182 children and adolescents (6–18 years of age) with diabetes and 160 nondiabetic control subjects. RESULTS —There were no differences between case and control subjects with respect to dental caries. Children with diabetes had significantly higher plaque and gingival inflammation levels compared with control subjects. The number of teeth with evidence of attachment loss (the hallmark of periodontal disease) was significantly greater in children with diabetes (5.79 ± 5.34 vs. 1.53 ± 3.05 in control subjects, unadjusted P < 0.001). When controlling for age, sex, ethnicity, gingival bleeding, and frequency of dental visits, diabetes remained a highly significant correlate of periodontitis, especially in the 12- to 18-year-old subgroup. In the case group, BMI was significantly correlated with destruction of connective tissue attachment and bone, but duration of diabetes and mean HbA 1c were not. CONCLUSIONS —Our findings suggest that periodontal destruction can start very early in life in diabetes and becomes more prominent as children become adolescents. Programs designed to promote periodontal disease prevention and treatment should be provided to young patients with diabetes. Footnotes A table elsewhere in this issue shows conventional and Système International (SI) units and conversion factors for many substances. Accepted November 4, 2005. Received July 21, 2005. DIABETES CARE