Expression of Receptor Activator of Nuclear Factor κB Ligand on Bone Marrow Plasma Cells Correlates with Osteolytic Bone Disease in Patients with Multiple Myeloma

Purpose : Increased bone resorption is a hallmark of multiple myeloma and is attributable to osteoclast activation. Recent studies showed that the receptor activator of nuclear factor κB ligand (RANKL) is the key mediator of osteoclastogenesis and plays a crucial role in bone destruction in malignan...

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Veröffentlicht in:	Clinical cancer research 2003-04, Vol.9 (4), p.1436
Hauptverfasser:	Ulrike Heider, Corinna Langelotz, Christian Jakob, Ivana Zavrski, Claudia Fleissner, Jan Eucker, Kurt Possinger, Lorenz C. Hofbauer, Orhan Sezer
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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