Tumor Necrosis Factor-α-induced Apoptosis in Prostate Cancer Cells through Inhibition of Nuclear Factor-κB by an IκBα “Super-Repressor”

Prostate cancer patients experiencing a relapse in disease often express high serum tumor necrosis factor-α (TNF-α) levels. Many androgen-insensitive prostate cancer cells are TNF-α insensitive because of the expression of antiapoptotic genes as part of the nuclear factor-κB (NF-κB) family of transc...

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Veröffentlicht in:	Clinical cancer research 2000-05, Vol.6 (5), p.1969
Hauptverfasser:	Heather J. Muenchen, Din-Lii Lin, Michael A. Walsh, Evan T. Keller, Kenneth J. Pienta
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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