N-Glycan-mediated Quality Control in the Endoplasmic Reticulum Is Required for the Expression of Correctly Folded δ-Opioid Receptors at the Cell Surface

A great majority of G protein-coupled receptors are modified by N -glycosylation, but the functional significance of this modification for receptor folding and intracellular transport has remained elusive. Here we studied these phenomena by mutating the two N-terminal N -glycosylation sites (Asn 18...

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Veröffentlicht in:	The Journal of biological chemistry 2008-10, Vol.283 (43), p.29086
Hauptverfasser:	Piia M. H. Markkanen, Ulla E. Petäjä-Repo
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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